Malignant Transformation of Endometriosis in the Ischioanal Fossa

Case Reports in Obstetrics and Gynecology
Jordan S KlebanoffMark G Cadungog

Abstract

We present the case of a 28-year-old nulliparous female with malignant transformation of an ectopic focus of endometriosis in the right ischioanal fossa. A 28-year-old nulliparous patient with a past medical history of polycystic ovarian syndrome (PCOS) was diagnosed with endometrioid adenocarcinoma in her right ischioanal fossa. Initially, patient presented to an emergency department and underwent a CT scan of the appendix to rule out appendicitis. A multiloculated cystic lesion adjacent to the right obturator internus muscle was found. She underwent surgical resection of the mass, which confirmed FIGO grade 2 endometrioid adenocarcinoma, followed by localized radiation therapy. Malignancy arising in endometriosis is rare, and the influence of PCOS on the rate of malignant transformation is not well established.

References

Jun 1, 1966·Clinical Obstetrics and Gynecology·R E ScullyJ F Barlow
Jun 25, 2010·The New England Journal of Medicine·Linda C Giudice
Oct 19, 2010·Cancer Causes & Control : CCC·Emily J FearnleyUNKNOWN Australian Ovarian Cancer Study Group and Australian National Endometrial Cancer Study Group
Dec 4, 2013·Diagnostic Pathology·Nikolaos MachairiotisChristodoulos Machairiotis
Feb 20, 2015·Biology of Reproduction·Jenny N FungGrant W Montgomery
Sep 13, 2016·Gynecologic and Obstetric Investigation·Mauro CozzolinoMaria Elisabetta Coccia
Dec 20, 2016·Seminars in Reproductive Medicine·Anne C Davis, Jeffrey M Goldberg
May 11, 2017·The New England Journal of Medicine·Michael S AnglesioIe-Ming Shih

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BETA
biopsy
contraception

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