Malignant transformation of fibrous dysplasia into angiosarcoma

Oral Radiology
Song Hee OhEui-Hwan Hwang

Abstract

Fibrous dysplasia (FD) is generally considered to be a benign disease that affects the bones, but it has potential to become malignant over time, generally several decades after its initial diagnosis. Radiation therapy can induce malignant transformation of FD; however, reports have indicated a few cases of malignant transformation of FD in the absence of radiation therapy. Angiosarcoma is a particularly rare type of cancer in the oral region, which accounts for less than 1% of all soft-tissue sarcomas. Herein, we reported a case of a 62-year-old man with monostotic FD of the left maxilla of over 50 years' duration that underwent malignant transformation into an epithelioid-type angiosarcoma. To the best of our knowledge, this is the first report of such case.

References

Feb 1, 1979·The American Journal of Surgical Pathology·K K Unni, D C Dahlin
Jul 1, 1981·Oral Surgery, Oral Medicine, and Oral Pathology·B B TothJ W Martin
Mar 1, 1994·Cancer·P RuggieriK K Unni
Mar 18, 2003·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Julie C Fanburg-SmithEsther L B Childers
Jan 1, 1964·The American Journal of the Medical Sciences·D T SCHWARTZ, M ALPERT
Jun 1, 1945·Annals of Surgery·B L Coley, F W Stewart
Sep 11, 2010·European Journal of Radiology·Piero PicciMario Mercuri
Jan 2, 2013·Archives of Pathology & Laboratory Medicine·Nicole D Riddle, Marilyn M Bui

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the Indian Medical Association
M MuralidharM R Raghavan
International Journal of Clinical Practice
A I VargheseW P Smith
© 2021 Meta ULC. All rights reserved