Malignant transformation of intracranial epidermoid cyst

British Journal of Neurosurgery
Eduardo Arnaldo Silva VellutiniJosé Marcus Rotta

Abstract

Intracranial epidermoid cysts (ECs) are rare, histologically benign, slow-growing, congenital neoplasms of central nervous system that may arise from retained ectodermal implants. Malignant transformation of an EC to squamous-cell carcinoma is rare; only 13 cases have been reported. We present the case of a 42-year-old woman presenting with left hemiparesis 18 months after performing partial resection of an epidermoid cyst of right middle and posterior fossa, whose pathological report revealed to be a malignant transformation of previous epidermoid tumor. Additionally, we performed pertinent literature review.

References

Nov 27, 2002·Journal of Neurosurgery·Michael J LinkJohn M Tew
Apr 4, 2006·Journal of Neuro-oncology·Kaoru TamuraKikuo Ohno
Oct 24, 2012·Journal of Korean Neurosurgical Society·Kyu-Hyon ChonHa-Young Choi

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Citations

Nov 29, 2015·Otolaryngologic Clinics of North America·Damien BressonSébastien Froelich
Aug 16, 2016·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Stylianos Pikis, Emil Margolin
Jun 9, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Robert J YawnMatthew L Carlson
Jun 8, 2018·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Tomu OkadaIkuma Kato
Feb 2, 2021·British Journal of Neurosurgery·Eduardo de Arnaldo Silva VellutiniLeonardo GIlmone Ruschel

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