Malignant tumor formation in dogs previously irradiated for acanthomatous epulis

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Margaret C McEnteeD E Thrall

Abstract

In this retrospective study of 57 dogs irradiated for oral acanthomatous epulis, 2 (3.5%) dogs developed a second tumor (sarcoma, osteosarcoma) in the radiation treatment field at 5.2 and 8.7 years after the end of radiation therapy. As opposed to previous reports, no second epithelial tumors developed in the radiation treatment field. There is a risk of radiation-induced carcinogenesis, but it appears that it is a relatively low risk and an event that occurs years after radiation therapy. Radiation-induced tumors are of more concern in younger dogs that undergo radiation therapy for tumors that are radioresponsive, such as acanthomatous epulis, where long-term survival is expected. The only statistically significant variable in the survival analysis was age, with dogs less than 8.3 years old having a significantly longer median overall survival (2322 days) than dogs older than 8.3 years (1106 days; P<0.0001).

References

Nov 1, 1978·Radiology·J H KimJ Cantin
Feb 1, 1992·Journal of Comparative Pathology·F J VerstraeteA Weber
Dec 1, 1991·Journal of Radiation Research·S A BenjaminA C Lee
Sep 1, 1990·International Journal of Radiation Oncology, Biology, Physics·M BarnesT Kinsella
Mar 1, 1990·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R GelmanJ R Harris
Sep 1, 1989·International Journal of Radiation Oncology, Biology, Physics·B E PowersS J Withrow
Jun 14, 1986·The Veterinary Record·R A WhiteN T Gorman
Jan 1, 1993·Journal of Comparative Pathology·D G Gardner, D C Baker
Mar 1, 1996·International Journal of Radiation Oncology, Biology, Physics·P A JohnstoneW F Sindelar
Oct 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J F KutteschL E Kun
Dec 5, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Merlin R HamreMichael P Mott
Apr 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Eric J Hall, Cheng-Shie Wuu
Aug 19, 2003·Archives of Biochemistry and Biophysics·Hiroshi OhshimaTomohiro Sawa
May 1, 1948·Cancer·W G CAHAN, H Q WOODARD

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Citations

Jun 18, 2014·ILAR Journal·Joelle M FengerWilliam C Kisseberth
Mar 4, 2014·The Veterinary Clinics of North America. Small Animal Practice·Amy J FultonFrank J M Verstraete
Dec 20, 2015·Journal of the American Veterinary Medical Association·Melissa A TollettErika L Krick
Jun 11, 2009·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Simona Mayer-StankeováBarbara Kaser-Hotz
Dec 13, 2006·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Sibylle Kneissl, Alexander Probst
Dec 11, 2007·Veterinary Surgery : VS·Daniel I SpectorRandy J Boudrieau
Feb 11, 2015·Veterinary and Comparative Oncology·E TreggiariL Blackwood
Feb 9, 2017·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Jennifer L MalmbergPaula A Schaffer
Feb 24, 2007·Veterinary Pathology·N D de BruijnT S G A M van den Ingh
Feb 19, 2019·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Koichi Nagata
Mar 11, 2006·Journal of the American Animal Hospital Association·Margaret C McEntee
Jan 5, 2010·Journal of the American Animal Hospital Association·Robert B Rebhun, Douglas H Thamm
Sep 26, 2020·Veterinary and Comparative Oncology·Francine van der Steen, Maurice Zandvliet
Apr 19, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Kenji HosoyaChieko Azuma
Jul 28, 2020·The Journal of Small Animal Practice·B NiemiecR Jouppi
Aug 17, 2015·Veterinary Sciences·Timothy M Fan, Chand Khanna
Jul 9, 2004·Journal of the American Animal Hospital Association·Nicole C NorthrupTracy L Gieger
Nov 3, 2020·Frontiers in Veterinary Science·Callie Blackford WindersStephanie Goldschmidt

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