Malignant tumors and chronic infections in the masticator space: preliminary assessment with in vivo single-voxel 1H-MR spectroscopy.

AJNR. American Journal of Neuroradiology
Q YuP Wang

Abstract

Differential diagnosis between malignant tumors and chronic infections in the masticator space remains challenging. The purpose of the study was to categorize various changes of both lesions by using single-voxel 1H-MR spectroscopy. Twenty-four masticator space lesions, 7 chronic infections, and 17 malignant tumors were assessed with 1H-MR spectroscopy before treatment procedures. The MR spectroscopic findings were compared with surgical and histopathologic results. Localization technique for 1H-MR spectroscopy was made by a point-resolved spectroscopy sequence at an echo time of 144 ms. Choline (Cho) signals (identified at 3.2 ppm) and Cho signal intensity-to-noise ratio (Cho/noise) were considered as evaluating criteria. All the lesions were found with 3 1H-MR spectroscopic types: type 1, lesions without Cho signals (3 chronic infections); type 2, lesions with Cho signals and Cho/noise ratio <3 (4 chronic infections and 4 malignant tumors); and type 3, lesions with Cho signals and Cho/noise ratio >3 (13 malignant tumors). The mean +/- SD of the Cho/noise ratio between chronic infections and malignant tumors was 2.31 +/- 0.19 and 5.76 +/- 3.29 (P < .01), respectively. In vivo single-voxel 1H-MR spectroscopy may be helpful in t...Continue Reading

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Citations

Mar 15, 2013·European Journal of Radiology·Ahmed Abdel Khalek Abdel Razek, Harish Poptani
Feb 7, 2014·Japanese Journal of Radiology·Ahmed Abdel Khalek Abdel Razek
Feb 20, 2013·Dento Maxillo Facial Radiology·A A K Abdel Razek, N Nada
Jul 28, 2013·Insights Into Imaging·T FernandesP M Som
Apr 20, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Pingzhong WangWenjing Zhu

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