PMID: 16614394Apr 15, 2006Paper

Malnutrition and energy restriction differentially affect viral immunity

The Journal of Nutrition
Barry W Ritz, Elizabeth M Gardner

Abstract

Protein-energy malnutrition is associated with a decrease in immunity and an increase in infectious disease. Both of these effects are exacerbated in aging. Conversely, energy restriction (ER) without malnutrition extends the lifespan in animals and retards the age-related decline in various parameters of immune function. Recent evidence suggests, however, that aged ER mice exhibit an increased mortality in response to primary influenza infection compared with age-matched controls. Underweight may contribute to this outcome due to an inability to meet the energy demands associated with the immune response to primary viral infection. The energetic costs of immune responsiveness must be considered in the undernourished aging population and emerging studies of ER in humans.

References

Jul 1, 1991·Journal of Gerontology·R B EffrosC Mitcheltree
May 1, 1990·The American Journal of Clinical Nutrition·D H SullivanD A Lipschitz
Nov 1, 1989·Journal of Gerontology·R Weindruch
Nov 1, 1981·Infection and Immunity·G J JakabC L Astry
Jun 1, 1995·Cellular Immunology·H P RedmondJ M Daly
Aug 1, 1997·The American Journal of Clinical Nutrition·N S Scrimshaw, J P SanGiovanni
Aug 1, 1997·The American Journal of Clinical Nutrition·B M Lesourd
Feb 26, 2000·Vaccine·R G Webster
May 9, 2000·Veterinary Microbiology·K Van Reeth
Feb 28, 2002·Best Practice & Research. Clinical Gastroenterology·M Pirlich, H Lochs
Nov 9, 2002·Microscopy Research and Technique·Haruyoshi YamazaIsao Shimokawa
Nov 9, 2002·Microscopy Research and Technique·Mark A LaneGeorge S Roth
Aug 26, 2003·The American Journal of Clinical Nutrition·Leonie K Heilbronn, Eric Ravussin
Nov 1, 1956·The Journal of Experimental Medicine·C C FLANIGAN, D H SPRUNT
Dec 31, 2003·Experimental Gerontology·Jamie L BargerRichard Weindruch
Mar 25, 2004·Trends in Immunology·Giuseppe Matarese, Antonio La Cava
Apr 21, 2004·Proceedings of the National Academy of Sciences of the United States of America·Luigi FontanaJohn O Holloszy
Jun 19, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gaëtan GavazziKarl-Heinz Krause
Sep 1, 2004·Trends in Microbiology·Melinda A BeckOrville A Levander
May 11, 2005·Immunological Reviews·Donna M Murasko, Jiu Jiang
May 12, 2005·Mechanisms of Ageing and Development·Edward J Masoro
Jun 29, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Elizabeth M Gardner
Aug 10, 2005·Experimental Gerontology·Janko Nikolich-Zugich, Ilhem Messaoudi
Oct 18, 2005·Mechanisms of Ageing and Development·Amie J Dirks, Christiaan Leeuwenburgh

❮ Previous
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Citations

Sep 28, 2007·Seminars in Dialysis·Theodoros EleftheriadisIoannis Stefanidis
Dec 24, 2008·Nature Reviews. Immunology·Kenneth DorshkindRobert A J Signer
Aug 4, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Hyunwon YangVishwa Deep Dixit
Dec 8, 2009·Bioscience, Biotechnology, and Biochemistry·Ken-ichi YamazakiMasanobu Nanno
Sep 8, 2009·Expert Reviews in Molecular Medicine·Richard G A FaragherElizabeth L Ostler
Aug 7, 2012·Immunity & Ageing : I & a·Iftikhar AlamGraham Pawelec
Mar 13, 2014·Scandinavian Journal of Immunology·M Godínez-VictoriaM E Drago-Serrano
Oct 10, 2013·Substance Use & Misuse·Fairlie McIlwraithRosa Alati
Dec 17, 2014·Journal of Nutrition and Metabolism·Mavil May C CervoLeonora N Panlasigui
Apr 3, 2015·The Journal of Nutrition·Daniel J RaitenUNKNOWN INSPIRE Consultative Group
Nov 26, 2016·Biogerontology·James J AndersonDavid J Sharrow
May 19, 2017·The Journal of Infectious Diseases·Anna M BramleyUNKNOWN Centers for Disease Control and Prevention Etiology of Pneumonia in the Community (EPIC) Study Team
Aug 9, 2020·Journal of Personalized Medicine·Anderson O FerreiraEli C F Dijkers
Aug 18, 2020·Developmental Medicine and Child Neurology·Noula GibsonAndrew C Wilson
Jun 15, 2011·Influenza and Other Respiratory Viruses·William A BlumentalsStephen Toovey
Oct 1, 2009·Acta Microbiologica Et Immunologica Hungarica·J OngrádiL Vértes
Mar 24, 2010·American Journal of Human Biology : the Official Journal of the Human Biology Council·Michael P MuehlenbeinAnn M Swartz
Feb 3, 2010·Perception·Vinet CoetzeeIan D Stephen
Jun 27, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·D T PhungC Chu
Sep 12, 2012·Rejuvenation Research·Andrew R Mendelsohn, James W Larrick
Jan 10, 2019·Frontiers in Psychology·Stefan de JagerVinet Coetzee
Jul 9, 2009·Age·Aamira IqbalElizabeth L Ostler
Mar 23, 2010·Perception·Vinet CoetzeeIan D Stephen
Nov 30, 2012·Proceedings. Biological Sciences·Markus J RantalaIndrikis Krams
Aug 9, 2017·Scientific Reports·Khutso G PhalaneVinet Coetzee
Jun 16, 2010·Immunity & Ageing : I & a·Joseph Ongrádi, Valéria Kövesdi
Sep 4, 2010·Antioxidants & Redox Signaling·Subramaniam Ponnappan, Usha Ponnappan
Jul 15, 2015·PloS One·José Antonio Muñoz-ReyesEnrique Turiegano
Jul 4, 2009·Journal of the American Geriatrics Society·Vibeke JuliebøTorgeir Bruun Wyller
Sep 24, 2018·Developmental and Comparative Immunology·George A Brusch, Dale F DeNardo

❮ Previous
Next ❯

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