Malnutrition and the Development of Periprosthetic Joint Infection in Patients Undergoing Primary Elective Total Joint Arthroplasty

The Journal of Arthroplasty
Kier BlevinsJavad Parvizi

Abstract

Although an abundance of literature exists linking malnutrition with infectious complications in surgical patients, there is little specifically examining the link between malnutrition and periprosthetic joint infection (PJI). This study evaluated the relationship between abnormal nutritional parameters and development of PJI in patients undergoing primary total joint arthroplasty (TJA). We retrospectively reviewed TJA patients from 2000 to 2016 with preoperative nutritional screening at a single institution. Any development of PJI at 2 years was assessed as the primary outcome. The Musculoskeletal Infection society criteria were used to define PJI. The association between the aforementioned nutritional markers and PJI was evaluated in a bivariate analysis followed by multivariate logistic regression. Performance for markers was assessed using receiver operator characteristic curves. Sensitivity and specificity were also compared. Multivariate analysis demonstrated that low albumin (adjusted odds ratio [OR], 4.69; 95% confidence interval [CI], 2.428-9.085; P < .001) and low hemoglobin (adjusted OR, 2.718; 95% CI, 1.100-2.718; P = .018) were significantly associated with PJI. Albumin had the highest specificity and (95% CI, 97.8...Continue Reading

Citations

Aug 23, 2019·Acta Cirúrgica Brasileira·Flávia Emi AkamatsuAlfredo Luiz Jacomo
Apr 16, 2019·Expert Opinion on Pharmacotherapy·Alicia Macias-ValcayoJaime Esteban
Jun 18, 2020·Current Reviews in Musculoskeletal Medicine·Lachlan M Batty, Brent Lanting
Aug 28, 2020·Journal of Orthopaedic Surgery·Vincent Wk ChanK Y Chiu
Aug 14, 2020·The American Journal of Tropical Medicine and Hygiene·Tarina C ParpiaJames A Platts-Mills
Feb 7, 2021·PM & R : the Journal of Injury, Function, and Rehabilitation·Yuta NanriMasashi Takaso
Mar 24, 2021·The Journal of Arthroplasty·Nick R JohnsonJesse E Otero
Apr 17, 2021·Curēus·Yüksel Uğur YaradılmışMurat Altay
Sep 17, 2021·Journal of Orthopaedic Surgery and Research·Yang TanLiaobin Chen

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