Malnutrition, Critical Illness Survivors, and Postdischarge Outcomes: A Cohort Study

JPEN. Journal of Parenteral and Enteral Nutrition
Kris M MogensenKenneth B Christopher

Abstract

We hypothesized that preexisting malnutrition in patients who survived critical care would be associated with adverse outcomes following hospital discharge. We performed an observational cohort study in 1 academic medical center in Boston. We studied 23,575 patients, aged ≥18 years, who received critical care between 2004 and 2011 and survived hospitalization. The exposure of interest was malnutrition determined at intensive care unit (ICU) admission by a registered dietitian using clinical judgment and on data related to unintentional weight loss, inadequate nutrient intake, and wasting of muscle mass and/or subcutaneous fat. The primary outcome was 90-day postdischarge mortality. Secondary outcome was unplanned 30-day hospital readmission. Adjusted odds ratios were estimated by logistic regression models adjusted for age, race, sex, Deyo-Charlson Index, surgical ICU, sepsis, and acute organ failure. In the cohort, the absolute risk of 90-day postdischarge mortality was 5.9%, 11.7%, 15.8%, and 21.9% in patients without malnutrition, those at risk of malnutrition, nonspecific malnutrition, and protein-energy malnutrition, respectively. The odds of 90-day postdischarge mortality in patients at risk of malnutrition, nonspecific m...Continue Reading

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Citations

Oct 24, 2019·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Sérgio Henrique LossLuciana Verçoza Viana
Jul 24, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Camila Neves RodriguesMaria Isabel Toulson Davisson Correia
Sep 17, 2020·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Selen AcehanCagdas Ince
May 29, 2018·Journal of Nutrition and Metabolism·Carlos Alfredo Galindo MartínOctavio Augusto Lescas Méndez
Jan 10, 2019·Journal of Clinical Medicine·Peter J M WeijsKenneth B Christopher
Nov 20, 2020·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·Ella Terblanche, Chris Remmington

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