Malondialdehyde, glutathione, and nitric oxide levels in Toxoplasma gondii seropositive patients.

The Korean Journal of Parasitology
Ulku KaramanNilgun Ulfet Daldal

Abstract

The aim of this study was to investigate the difference in the serum malondialdehyde (MDA), glutathione (GSH), and nitric oxide (NO) levels between normal and T. gondii-infected patients. To this end, MDA, GSH, and NO levels in the sera of 37 seropositive patients and 40 participants in the control group were evaluated. In Toxoplasma ELISA, IgG results of the patient group were 1,013.0 +/- 543.8 in optical density (mean +/- SD). A statistically significant difference was found between patients and the control group in terms of MDA, GSH, and NO levels. A decrease in GSH activity was detected, while MDA and NO levels increased significantly. Consequently, it is suggested that the use of antioxidant vitamins in addition to a parasite treatment shall prove useful. The high infection vs control ratio of MDA and NO levels probably suggests the occurrence as a mechanism of tissue damage in cases of chronic toxoplasmosis. Moreover, it is recommended that the patient levels of MDA, GSH, and NO should be evaluated in toxoplasmosis.

Citations

Nov 15, 2011·Annual Review of Pathology·Federica SotgiaMichael P Lisanti
Jul 14, 2012·Parasitology Research·Ayse Basak EnginNeslihan Bukan
Oct 9, 2015·Parasitology Research·Rasha F MadySamar Elachy
Feb 9, 2011·The International Journal of Biochemistry & Cell Biology·Ubaldo E Martinez-OutschoornMichael P Lisanti
Mar 20, 2016·Experimental Parasitology·Xiaochuan ZhangChunmei Jin
Jul 9, 2011·Chemico-biological Interactions·Thankamani Marar
May 18, 2016·The Korean Journal of Parasitology·Seon-Ju YeoHyun Park
Mar 12, 2016·International Journal of Immunopathology and Pharmacology·Gungor Cagdas Dincel, Hasan Tarik Atmaca
Mar 14, 2018·Parasite : Journal De La Société Française De Parasitologie·Mlatovi DégbéMessanvi Gbeassor
Apr 27, 2017·Asian Pacific Journal of Tropical Medicine·Mervat MashalyAbeer A El Henawy
Jun 3, 2021·International Journal of Molecular Sciences·Karolina Szewczyk-GolecCelestyna Mila-Kierzenkowska
Jul 5, 2021·The Korean Journal of Parasitology·Run-Hui ZhangChun-Mei Jin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.