Mamillary body in the rat: topography and synaptology of projections from the subicular complex, prefrontal cortex, and midbrain tegmentum

The Journal of Comparative Neurology
G V Allen, D A Hopkins

Abstract

The retrograde and anterograde transport of horseradish peroxidase conjugated to wheat germ agglutinin (WGA-HRP) has been used to trace afferent connections of the rat mamillary body (MB) at the light and electron microscopic levels. Injections of WGA-HRP into different parts of the MB resulted in heavy retrograde labeling in the subicular complex, medial prefrontal cortex, and dorsal and ventral tegmental nuclei. Injections of WGA-HRP into each of these brain regions, respectively, resulted in anterograde labeling with specific distributions and characteristic synaptic organizations in the MB. Projections from the rostrodorsal and caudoventral subiculum terminated in a topographically organized laminar fashion in the medial mamillary nucleus bilaterally, whereas afferent projections from the presubiculum and parasubiculum terminated only in the lateral mamillary nucleus. Labeled axon terminals which originated from the subicular complex were characterized by round vesicles and formed asymmetric synaptic junctions with small-diameter dendrites and dendritic spines in the medial and lateral mamillary nuclei. Projections from the prefrontal cortex originated mainly in the infralimbic area and to a lesser degree in the prelimbic a...Continue Reading

References

Feb 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Jan 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Mar 25, 1977·Brain Research·R C Meibach, A Siegel
May 1, 1977·Experimental Neurology·J RosenstockE Greene
Dec 15, 1977·The Journal of Comparative Neurology·J A Cruce
Apr 1, 1976·Experimental Neurology·A A FaiersG J Mogenson
Apr 15, 1976·The Journal of Comparative Neurology·R M Beckstead
Dec 1, 1987·Brain Research Bulletin·R R Terreberry, E J Neafsey
Sep 1, 1988·The Journal of Comparative Neurology·G V Allen, D A Hopkins
Oct 1, 1986·Physiology & Behavior·J P Kroon, A L Riley
Jan 1, 1985·Experimental Brain Research·J P Aggleton, M Mishkin
Oct 1, 1969·Electroencephalography and Clinical Neurophysiology·D JinnaiK Kobayashi
Jul 23, 1971·Brain Research·P L ParmeggianiP Lenzi
Jan 1, 1967·Experimental Brain Research·K Uchizono
Mar 1, 1966·Brain : a Journal of Neurology·G RaismanT P Powell
Feb 1, 1966·The Journal of Experimental Zoology·R D Lisk
Jul 1, 1983·Experimental Neurology·E J HolmesN Butters
Sep 17, 1984·Brain Research·R LiuG Wickern
Oct 20, 1984·The Journal of Comparative Neurology·M Seki, K Zyo
Nov 1, 1984·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D B RyeB H Wainer
Jan 1, 1980·Acta Anatomica·K Watanabe, E Kawana
Nov 1, 1952·Electroencephalography and Clinical Neurophysiology·P D MACLEAN

❮ Previous
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Citations

May 1, 1993·Neuroscience·A Gonzalo-RuizR F Spencer
Jan 1, 1996·Brain Research Bulletin·J S TaubeR W Stackman
Feb 26, 2000·Neuropsychologia·Y D Van der WerfJ Jolles
Oct 1, 1996·Pharmacology, Biochemistry, and Behavior·S RubioJ L Arias
Dec 26, 2001·Brain Research. Brain Research Reviews·G D PetrovichL W Swanson
Jul 17, 1999·Brain Research. Brain Research Reviews·T van GroenJ M Wyss
Nov 14, 2002·Behavioural Brain Research·Thomas van GroenJ Michael Wyss
Jul 14, 1999·Behavioural Brain Research·L J SantínJ L Arias
Feb 14, 1998·Progress in Neurobiology·V Sziklas, M Petrides
Mar 3, 1999·The European Journal of Neuroscience·C C StichelH W Müller
Jan 1, 1990·The European Journal of Neuroscience·Menno P. WitterHenk J. Groenewegen
Mar 8, 2007·Annual Review of Neuroscience·Jeffrey S Taube
Apr 16, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benjamin J ClarkJeffrey S Taube
Jun 28, 2013·ELife·Seralynne D Vann
Jun 21, 2001·Proceedings of the National Academy of Sciences of the United States of America·J P JohansenB H Manning
Oct 7, 2014·Psychiatry Research·Lisanne Michelle JenkinsRoy Peter Caspar Kessels
Jul 17, 2003·The Journal of Comparative Neurology·Francisco E Olucha-BordonauFrancisco Martínez-Soriano
Nov 26, 2005·The European Journal of Neuroscience·John P AggletonRichard C Saunders
Aug 11, 2011·The Journal of Comparative Neurology·Richard C SaundersJohn P Aggleton
May 4, 2010·The Journal of Comparative Neurology·Nicholas F WrightJohn P Aggleton

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