Abstract
The cytogenetic analysis of five mammary epithelial hyperplasias is reported. Only two cases had clonal chromosome alterations. Structural alterations involved chromosomes 1 and 5. Numerical alterations involved chromosomes X, 1, 6, 9, and 19. In four cases, the modal number was in the diploid range, and one case was tetraploid. The study of benign proliferations and their comparison with the chomosome alterations of their malignant counterparts could lead to a better understanding of the genes acting solely in cell proliferation and those that cause these cells to undergo malignant transformation and to become invasive.
References
Jan 1, 1977·Human Pathology·J S Meyer
May 1, 1977·Journal of the National Cancer Institute·J R MastersJ J Scarisbrick
Oct 1, 1992·Cancer Genetics and Cytogenetics·C F StephensonA A Sandberg
Jan 1, 1992·Journal of Cellular Biochemistry. Supplement·D L Page, W D Dupont
May 1, 1991·Genes, Chromosomes & Cancer·G CalabreseG Palka
Nov 1, 1991·Human Genetics·G DicksonF S Walsh
Apr 1, 1991·Mutation Research·A A Sandberg
May 1, 1990·Genes, Chromosomes & Cancer·C Saint-RufB Dutrillaux
May 1, 1989·Cancer Genetics and Cytogenetics·K V Nielsen, P Briand
May 16, 1985·Nature·G Klein, E Klein
Jan 1, 1987·Cancer Genetics and Cytogenetics·S M HillM A Hultén
Aug 1, 1987·Cancer Genetics and Cytogenetics·A D Ferti-Passantonopoulou, A D Panani
Jan 1, 1988·Cytogenetics and Cell Genetics·S PathakP C Sacks
Jan 1, 1986·Breast Cancer Research and Treatment·E GebhartW Schmidt
Jan 16, 1987·Science·J M Bishop
Dec 1, 1986·The Journal of Infectious Diseases·M L KachmerJ P Myers
Oct 1, 1984·Cancer Genetics and Cytogenetics·C S RodgersM A Hultén
Feb 1, 1984·Cancer Genetics and Cytogenetics·A Ferti-PassantonopoulouS Raptis
Aug 1, 1981·British Journal of Cancer·D J Ferguson, T J Anderson
Jun 1, 1981·Human Pathology·J J Yunis
Oct 9, 1980·The New England Journal of Medicine·M B Sporn, G J Todaro
Jan 1, 1993·Advances in Cancer Research·M J van de Vijver
Apr 1, 1993·Trends in Genetics : TIG·B Vogelstein, K W Kinzler
Citations
May 30, 2002·Cancer Genetics and Cytogenetics·Lydia NakopoulouPanayiotis Davaris
Dec 22, 1999·Cancer Genetics and Cytogenetics·D A CornélioI J Cavalli
May 17, 2000·Cancer Genetics and Cytogenetics·R R BurbanoC Casartelli