Mammographic tumour appearance and triple-negative breast cancer associated with long-term prognosis of breast cancer death: a Swedish Cohort Study

Cancer Epidemiology
Huei-Shian TsauKing-Jen Chang

Abstract

Numerous studies have paid attention to the role of the triple-negative marker in the prognosis of breast cancer, but very few studies have combined mammographic phenotypes with the triple-negative marker to assess their relevance to the long-term prognosis of breast cancer. The current study aims to assess the respective contributions of both mammographic tumour appearance and the triple-negative marker, and their possible interactions, on the long-term survival of breast cancer, taking into account the prognostic factors already established. A retrospective cohort of 498 breast cancer patients was enrolled at Falun Central Hospital, Sweden, between 1996 and 1998, and information on immunohistochemical markers and histological tumour distribution in these patients was collected. This cohort - together with prior information on conventional tumour attributes and mammographic tumour features from 1968 to 1995 - was formed by the Bayesian method and was followed over time until the end of 2011. After considering tumour attributes, histological tumour distribution, and triple-negative cancer, two mammographic tumour features - casting type (adjusted hazard ratio, aHR=3.47, 2.21-5.53) and architectural distortion (aHR=4.43, 2.02-9....Continue Reading

References

Oct 22, 2005·Nature Reviews. Cancer·Joseph A Ludwig, John N Weinstein
Nov 23, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bruce G HafftyDeborah Toppmeyer
Dec 6, 2006·Cancer·Emad A RakhaIan O Ellis
Jul 26, 2007·BMC Cancer·Marc TischkowitzWilliam D Foulkes
Aug 3, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Rebecca DentSteven A Narod
May 26, 2009·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Hirotaka IwaseTakuji Iwase
Jun 10, 2009·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Futoshi Akiyama, Hirotaka Iwase
Dec 17, 2010·Annals of Surgical Oncology·Tibor Tot, Gyula Pekár
Apr 2, 2011·International Journal of Clinical Oncology·Kuo Yao-LungChang Tsai-Wang
Aug 18, 2012·Asia-Pacific Journal of Clinical Oncology·Hong LingZhi-Min Shao
Mar 22, 2014·Molecular and Clinical Oncology·Na YuanXinhan Zhao
Mar 25, 2014·Breast Cancer Research and Treatment·Matthew P BanegasScarlett L Gomez

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer Triple-N

Breast cancer cells have receptors for estrogen, progesterone, HER2 receptors (also called ERBB2). Triple-negative breast cancers do not have any of these receptors. Here are the latest discoveries pertaining to triple-negative breast cancers.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.