Man against machine: diagnostic performance of a deep learning convolutional neural network for dermoscopic melanoma recognition in comparison to 58 dermatologists

Annals of Oncology : Official Journal of the European Society for Medical Oncology
H A HaenssleReader study level-I and level-II Groups

Abstract

Deep learning convolutional neural networks (CNN) may facilitate melanoma detection, but data comparing a CNN's diagnostic performance to larger groups of dermatologists are lacking. Google's Inception v4 CNN architecture was trained and validated using dermoscopic images and corresponding diagnoses. In a comparative cross-sectional reader study a 100-image test-set was used (level-I: dermoscopy only; level-II: dermoscopy plus clinical information and images). Main outcome measures were sensitivity, specificity and area under the curve (AUC) of receiver operating characteristics (ROC) for diagnostic classification (dichotomous) of lesions by the CNN versus an international group of 58 dermatologists during level-I or -II of the reader study. Secondary end points included the dermatologists' diagnostic performance in their management decisions and differences in the diagnostic performance of dermatologists during level-I and -II of the reader study. Additionally, the CNN's performance was compared with the top-five algorithms of the 2016 International Symposium on Biomedical Imaging (ISBI) challenge. In level-I dermatologists achieved a mean (±standard deviation) sensitivity and specificity for lesion classification of 86.6% (±9...Continue Reading

References

Oct 1, 1987·Journal of the American Academy of Dermatology·H PehambergerK Wolff
Dec 26, 2001·Archives of Dermatology·S W MenziesW H McCarthy
Jan 17, 2007·Archives of Dermatology·Howard K Koh
Jun 22, 2011·Archives of Dermatology·Scott W MenziesKaren Byth
Aug 16, 2012·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Rahil GarnaviJames Bailey
Nov 28, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·G SalerniH Kittler
Jul 3, 2013·The British Journal of Dermatology·V Nikolaou, A J Stratigos
Mar 25, 2014·IEEE Transactions on Bio-medical Engineering·Jeffrey GlaisterDavid A Clausi
Sep 21, 2015·Journal of the American Academy of Dermatology·Laura K FerrisMahadev Satyanarayanan

❮ Previous
Next ❯

Citations

May 31, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V J Mar, H P Soyer
Jul 12, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H A Haenssle, C Fink
Nov 6, 2018·Journal of Medical Systems·Christine FinkHolger A Haenssle
Aug 31, 2018·Sangyō eiseigaku zasshi = Journal of occupational health·Mitsuo UchidaHiroshi Koyama
Jan 22, 2019·International Journal of Audiology·Richard M McKearney, Robert C MacKinnon
Jan 30, 2019·Advances in Health Sciences Education : Theory and Practice·Matt SibbaldGeoffrey Norman
Feb 5, 2019·The British Journal of Dermatology·M Janda, H P Soyer
Jan 18, 2019·Lasers in Surgery and Medicine·Anna-Marie HoskingDaniel S Gareau
Feb 20, 2019·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Nicolas Maillard, Christophe Mariat
May 16, 2019·QJM : Monthly Journal of the Association of Physicians·P W VinnyV Y Vishnu
May 28, 2019·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E Deutsch, N Paragios
Jun 1, 2019·International Journal of Dermatology·Eva Hulstaert, Lars Hulstaert
May 16, 2019·Journal of General Internal Medicine·Steven Y LinChristine A Sinsky
Sep 7, 2019·Journal of Neurosurgery. Spine·Kevin T HuangOmar M Arnaout
Mar 7, 2019·American Journal of Physical Medicine & Rehabilitation·Dustin Anderson
Jun 20, 2019·JAMA Dermatology·Vincent DickPhilipp Tschandl
May 24, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V J Mar, H P Soyer
Aug 23, 2019·Neurology and Therapy·Aly Al-Amyn VallianiEric Karl Oermann
Dec 20, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·C FinkH A Haenssle
Aug 20, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·Y ChungN A Kukutsch
Jan 11, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·S LeeS Yang
Aug 20, 2019·Chinese Medical Journal·Cheng-Xu LiYong Cui
Jan 4, 2020·Radiological Physics and Technology·Hiroshi Fujita
Sep 22, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·S ZhaoX Chen
Oct 28, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·N Moellhoff, R E Giunta
Nov 30, 2019·BMJ Health & Care Informatics·Mark SujanNick Reynolds
Apr 8, 2020·Dermatology and Therapy·Stephanie ChanWilson Liao
Oct 5, 2019·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Samer EllahhamMecit Can Emre Simsekler
Aug 22, 2020·Yearbook of Medical Informatics·Xosé M Fernández
Aug 22, 2020·Yearbook of Medical Informatics·Ashley C GriffinArlene E Chung
Aug 26, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Heinz KutznerTitus J Brinker
Sep 6, 2019·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Andreas BlumIris Zalaudek
Jul 29, 2020·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A BlumP Tschandl

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.