Management framework paradigms for disorders of sex development

Archives of Endocrinology and Metabolism
Mariana Telles-SilveiraClaudio E Kater

Abstract

Until 2005, questions regarding medical treatment and diagnostic information on Disorders of Sex Development (DSD) were not systematically discussed with both the patients and their families; however, the way these patients are currently treated have been changing with time. Interventional changes in the clinical-psychotherapeutic-surgical areas of DSD determine not only different medical recommendations but also help to place the patient and the family into the decisional process of therapy. We must consider two paradigmatic periods that have influenced and transformed the clinical management framework of patients with DSD: a) The "Money era" (1955), which emphasized the role of the gonads as the diagnostic criterion, having the environment as determinant of the sex identity; and b) The Chicago Consensus (2005) phase, in which the role of genetics and molecular biology was critical for an early identification, as well as in building a proper sex identity, emphasizing ethical questions and the "stigma culture". In addition, recent data have focused on the importance of interdisciplinarity and statements on questions concerning Human Rights as key factors in treatment decision making. Despite each of these management models bein...Continue Reading

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Citations

Jun 9, 2016·São Paulo Medical Journal = Revista Paulista De Medicina·Mariana Telles-SilveiraClaudio Elias Kater
Apr 8, 2017·Case Reports in Endocrinology·Filippa PritsiniAssimina Galli-Tsinopoulou
Dec 23, 2020·Problemy e̊ndokrinologii·Nikolay D ShiryaevVladimir V Sizonov

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