Management of a parturient with high-grade osteosarcoma of the proximal femur: a multidisciplinary approach

International Journal of Obstetric Anesthesia
A A QuayeL R Leffert

Abstract

Osteosarcoma is the most common primary malignant bone tumor, yet it is exceedingly rare in pregnancy. We present a case of a 33-year-old multiparous woman diagnosed with high-grade osteosarcoma during the third trimester of pregnancy. A plan was formulated to perform cesarean delivery at 33 weeks of gestation under spinal anesthesia, and, in subsequent surgery, radical femoral neck resection with limb salvage and adjuvant chemotherapy. The outcome was a healthy newborn baby boy and a disease-free mother. This case highlights the benefits of multidisciplinary planning: balancing the needs of the developing fetus with those of the mother, mitigating the risk of pathologic fracture and ensuring timely oncologic therapy.

References

Mar 2, 1999·Acta Oncologica·O Merimsky, A Le Cesne
Jun 17, 2003·Clinical Obstetrics and Gynecology·Joseph R Ritchie
Apr 28, 2004·Journal of Pediatric Hematology/oncology·Wako NakajimaKyoji Okada
Aug 5, 2004·Obstetrics and Gynecology·Cynthia MaxwellDan Farine
Jun 5, 2007·Current Opinion in Oncology·Stefano Ferrari, Emanuela Palmerini
Jan 18, 2008·Obstetrical & Gynecological Survey·Micah Warren SmithL Daniel Wurtz

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