Management of acute bronchiolitis: can evidence based guidelines alter clinical practice?

Thorax
J BarbenSwiss Paediatric Respiratory Research Group

Abstract

Acute bronchiolitis is the most common lower respiratory tract infection in infants and there is no evidence that drug treatment alters its natural course. Despite this, most Swiss paediatricians reported in 2001 prescribing bronchodilators and inhaled corticosteroids (ICS). This situation led to the creation of national guidelines followed by a tailored implementation programme. The aim of this study was to examine if treatment practices changed after the implementation of the new guidelines. A questionnaire on treatment of bronchiolitis was sent to all Swiss paediatricians before (2001) and after (2006) creation and implementation of national guidelines (2003-2005). Guidelines were created in collaboration with all paediatric pulmonologists and implemented carefully using a multifaceted approach. Questionnaires were returned by 541 paediatricians (58%) in 2001 and by 639 (54%) in 2006. While both surveys showed a wide variation in the treatment of bronchiolitis between physicians, reported drug prescription decreased significantly between the two surveys. For outpatients, general use (for all patients) of bronchodilators dropped from 60% to 23%, and general use of ICS from 34% to 6%. For inpatients, general use of bronchodila...Continue Reading

Citations

Oct 6, 2010·Italian Journal of Pediatrics·Daniele De BrasiLuciano de Seta
Mar 4, 2014·PloS One·Joanna MurrayUNKNOWN Medicines for Neonates Investigator Group
Jan 1, 2012·Hospital Pediatrics·Russell J McCullohBrian Alverson
Jan 28, 2014·Archives of Disease in Childhood·Joanna MurrayMike Sharland
May 27, 2014·European Journal of Pediatrics·Fabiola StollarConstance Barazzone Argiroffo
Mar 1, 2010·Surgical Pathology Clinics·Timothy Craig Allen
Feb 1, 2015·Paediatric Respiratory Reviews·Jose A Castro-RodriguezMonica P Sossa-Briceño
Oct 11, 2012·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Shawn RalstonMichael Ryan
Apr 30, 2014·Acta Paediatrica·Minna MecklinMatti Korppi
Nov 26, 2015·Pediatric Pulmonology·Ricardo M FernandesTeresa Bandeira
Jul 15, 2015·Journal of Evaluation in Clinical Practice·Maher AboudaAli Ben Kheder
Sep 3, 2014·PloS One·Sven SchmiedlMarietta Rottenkolber
Jan 13, 2009·Pediatric Clinics of North America·Mark L Everard
May 14, 2016·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Christopher L Carroll The Northeast Pediatric Critical Care Research Consortium
Oct 2, 2014·The European Respiratory Journal·Jürg Barben, Claudia E Kuehni
Jun 5, 2013·The Cochrane Database of Systematic Reviews·Ricardo M FernandesLisa Hartling
Feb 3, 2016·The Cochrane Database of Systematic Reviews·Marta Roqué i FigulsJordi Vilaró
Jan 13, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Philipp SchuetzJohn E Schneider
May 28, 2019·Clinical Pediatrics·Andrea V Rivera-SepulvedaRachel L Charney
Aug 6, 2016·Therapeutic Advances in Respiratory Disease·Ricardo Henao-VilladaCarlos E Rodríguez-Martínez
May 21, 2018·Administration and Policy in Mental Health·Brooke LiflandArti D Desai
Jun 17, 2011·The Cochrane Database of Systematic Reviews·Lisa HartlingRicardo M Fernandes
May 1, 2021·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Timothy J D OhlsenEric R Coon
May 6, 2010·Archives of Pathology & Laboratory Medicine·Timothy Craig Allen
Feb 12, 2017·Pediatrics·Mersine A BryanRita Mangione-Smith
Dec 1, 2017·Pediatrics·Suzanne SchuhUNKNOWN Pediatric Emergency Research Networks (PERN)
Jul 15, 2020·Pediatrics·Amy ZipurskyUNKNOWN PEDIATRIC EMERGENCY RESEARCH NETWORKS (PERN)
Aug 22, 2018·Pediatrics·Gabrielle FreireUNKNOWN Pediatric Emergency Research Networks (PERN)
Dec 11, 2021·Pediatric Pulmonology·Katharina HartogJürg Barben

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved