Management of autoimmune diseases after haematopoietic stem cell transplantation

British Journal of Haematology
Andreas HolbroThomas Daikeler

Abstract

Autologous and allogeneic haematopoietic stem cell transplantation (HSCT) is an option for the treatment of malignant and non-malignant diseases, including the severe autoimmune diseases. Intriguingly, the 'new' autoimmunity developing after transplantation is a constantly recognized phenomenon, which has to be differentiated from original disease relapse, toxicity, infection and graft-versus-host disease. The reported autoimmune diseases occurring in this setting are mainly antibody-associated and organ-specific, with scarce evidence in support for specific treatment options. This review focuses on current concepts on the pathogenesis, the available data on incidence, risk factors, manifestations and treatment of post-HSCT autoimmune diseases.

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Apr 6, 2013·Thyroid : Official Journal of the American Thyroid Association·Akash SinhaTim Cheetham
Sep 30, 2014·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Meng WangAleksandar Mijovic
Jul 16, 2014·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Nada HamadVikas Gupta
Jul 31, 2014·Pediatric Transplantation·Hideaki UekiShosuke Sunami
Nov 8, 2014·British Journal of Haematology·Paola CiprianiRoberto Giacomelli
Nov 28, 2013·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Maura FaraciUNKNOWN Italian Association of Paediatric Haematology and Oncology
Apr 21, 2016·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Zhuoyan LiBipin N Savani
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Dec 8, 2015·Hematology·Andreas Holbro, Jakob R Passweg
Nov 12, 2016·Proceedings of the National Academy of Sciences of the United States of America·Nora MirzaSebastian P Haen
Sep 12, 2018·Expert Review of Clinical Immunology·Wilma BarcelliniAnna Zaninoni
Aug 8, 2017·Bone Marrow Transplantation·J H ChewningF D Goldman
Apr 4, 2017·British Journal of Haematology·Quentin A HillUNKNOWN British Society for Haematology Guidelines
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Mar 30, 2021·Transplantation and Cellular Therapy·Iman ShifaJan Storek
Sep 4, 2020·Hematology/oncology and Stem Cell Therapy·Uroosa Ibrahim, Alla Keyzner

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