Management of BK Polyomavirus Infection in Kidney and Kidney-Pancreas Transplant Recipients: A Review Article

Infectious Disease Clinics of North America
Nissreen ElfadawyNagaraju Sarabu

Abstract

BK virus (BKV) can cause graft dysfunction or failure in kidney transplant recipients and hemorrhagic cystitis in allogeneic hematopoietic stem cell transplant patients. BKV-associated nephropathy (BKVAN) emerged as a common complication in the late 1990s, probably due to the introduction of potent immunosuppressive agents. BKVAN occurred in up to 5% of kidney transplant recipients, with graft failure in up to 70%. Since universal implementation of effective screening and treatment strategies, BKV is no longer a common cause of graft failure; reported graft loss is only 0% to 5%. This article briefly describes BK virology, epidemiology, diagnosis, and management.

Citations

Mar 15, 2019·The Journal of Infectious Diseases·Susanna K TanBenjamin A Pinsky
May 21, 2020·Current Transplantation Reports·Aaron KavianiDavid A Axelrod
Dec 9, 2020·Antimicrobial Agents and Chemotherapy·Nichodemus O OnwubikoHeinz Peter Nasheuer
Apr 19, 2021·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Irene Muñoz-GallegoMaría Dolores Folgueira
Apr 29, 2021·Transplantation·Thida Maung MyintGermaine Wong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

BK Virus Infection

BK virus infection is a significant complication of modern immunosuppression used in kidney transplantation. Discover the latest research on BK virus infection here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.