Management of Brain Abscess: Changing Trend and Experience in Enugu, Nigeria

Nigerian Journal of Surgery : Official Publication of the Nigerian Surgical Research Society
C A NdubuisiIgnatius I Ozor

Abstract

Intracranial abscess remains a significant health-care problem. Its causes, diagnosis, treatment, and outcome are changing. This paper reviewed the demography, examined new trends, and compared outcomes with different treatment options. Retrospective analysis of intracranial abscesses managed at Memfys Hospital, Enugu (2004-2014) and University of Nigeria Teaching Hospital (2009-2014). Patients were followed up for at least 6 months. All patients had neuroimaging before intervention. Microscopy and culture were performed for the specimens. Intravenous antibiotics were given for 2 weeks before conversion to oral. Seventy-nine parenchymal abscesses (eight cases per year) were managed. Peak age was the second decade of life. Previous head injury (21.5%) and meningitis (16.5%) were the most common predisposing factors. The frontal lobe was most common anatomical location (32%). Only 24% had positive culture result. Three cases were fungal infections. Seventy percent of patients managed with burr hole drainage and 37.5% of craniotomy made complete recovery. Overall, 58% of patients made complete recovery, whereas 19.0% died. Nine percent of cases died before definitive intervention. Among the 24% of patients that presented in coma, ...Continue Reading

Citations

Jul 14, 2018·Journal of Neurosurgery. Pediatrics·Marlina E LovettNicole F O'Brien
Feb 9, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Oluwatosin E OlorunmoteniIbitoye Samuel
Apr 26, 2020·Current Opinion in Otolaryngology & Head and Neck Surgery·Mahmood F BhuttaWalter D Johnson

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An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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Brain abscess is an accumulation of pus caused by inflammation and infected materials in the brain. Symptoms include fever, headache, seizures and other neurological problems. Discover the latest research on brain abscess today.

Antifungals

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