Management of cerebral vasospasm

Neurosurgical Review
R Loch Macdonald

Abstract

Cerebral vasospasm is delayed narrowing of the large arteries of the circle of Willis occurring 4 to 14 days after aneurysmal subarachnoid hemorrhage (SAH). It is but one cause of delayed deterioration after SAH but, in general, is the most important potentially treatable cause of morbidity and mortality after SAH. Development of vasospasm is best predicted by the volume, location, persistence and density of subarachnoid clot early after SAH. Diagnosis is made by catheter angiography or, with less accuracy, by computed tomographic angiography, transcranial Doppler ultrasound or other methods. Treatment remains problematic because it is expensive, time-consuming, associated with substantial risk and largely ineffective. Treatment includes optimization of factors that affect cerebral blood flow and metabolism, systemic administration of nimodipine, hemodynamic therapy and pharmacologic and mechanical angioplasty.

References

Jan 1, 1979·Clinical Neurosurgery·S J Peerless
Feb 1, 1978·Journal of Neurosurgery·B WeirC Rothberg
Dec 1, 1992·Journal of Neurosurgery·N F KassellW S Cail
Dec 1, 1991·Stroke; a Journal of Cerebral Circulation·E F WijdicksJ A Nathanson
Sep 1, 1991·Journal of Neurosurgery·R L MacdonaldK Kanamaru
May 1, 1990·Journal of Neurosurgery·J W PetersonN T Zervas
Apr 1, 1990·Journal of Neurosurgery·M R MaybergD H Bark
Nov 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·G M TeasdaleJ C De Villiers
Jan 1, 1985·Journal of Neurosurgery·B VoldbyF T Jensen
Nov 1, 1963·The American Journal of Physiology·W W OppeltD P Rall
Sep 1, 1982·Neurologia Medico-chirurgica·H OhtaZ Ito
Mar 17, 1983·The New England Journal of Medicine·G S AllenC R Transou
Jan 1, 1984·Journal of Neurosurgery·R AaslidH Nornes

❮ Previous
Next ❯

Citations

Jun 14, 2008·Der Anaesthesist·M J Merkel, A M Brambrink
Oct 17, 2008·Neurocritical Care·Salvatore SalomoneJohn Randall Sims
Dec 5, 2013·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Iván Sánchez Fernández, Tobias Loddenkemper
Aug 24, 2012·Journal of Neurointerventional Surgery·Naif M Alotaibi, Giuseppe Lanzino
Nov 10, 2012·Cerebrovascular Diseases Extra·Eric A SchmidtFrançois Chollet
Dec 18, 2012·Medical Gas Research·Christoph J GriessenauerR Shane Tubbs
Dec 6, 2008·Neurological Research·Alexander Y Zubkov, Alejandro A Rabinstein
Nov 13, 2010·Intensive Care Medicine·Elisa R ZanierNino Stocchetti
Oct 9, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Alireza MansouriSunit Das
Aug 14, 2010·AJNR. American Journal of Neuroradiology·J V SehyC J Moran
Oct 17, 2008·Expert Opinion on Investigational Drugs·R Loch Macdonald
Mar 19, 2014·Neurología : publicación oficial de la Sociedad Española de Neurología·G Alcalá-CerraUNKNOWN en representación del Grupo de Investigación en Ciencias de la Salud y Neurociencias (CISNEURO)
Jul 16, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Sanser GulBektaş Acikgoz
Mar 2, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Sanser GulBektaş Acikgoz
Oct 16, 2007·Annales Françaises D'anesthèsie Et De Rèanimation·B TavernierB Riegel
Apr 3, 2016·Clinical Neurology and Neurosurgery·Christine HammerPascal Jabbour
Oct 1, 2013·Progress in Neurobiology·Sheng ChenJohn H Zhang
Apr 20, 2013·Functional Neurology·Mauricio MandelGerson Chadi
Dec 5, 2012·Journal of Cerebrovascular and Endovascular Neurosurgery·Sang-Won JungMan-Bin Yim
Jul 21, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·P L Rodríguez GarcíaD Rodríguez García
Jul 21, 2010·Neurosurgery·Chia-Hung ChouMichael J Alexander

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.