Management of choroidal naevomelanocytic lesions: feasibility and safety of a virtual clinic model

The British Journal of Ophthalmology
Konstantinos BalaskasMandeep S Sagoo

Abstract

Choroidal naevomelanocytic lesions are often identified as an incidental finding by community optometrists and referred for expert evaluation in hospital eye units or specialist ocular oncology centres. Optimal management strategy is undecided and most centres err on the side of caution. Our aim was to test a virtual model of service delivery relying on interpretation of imaging test results by non-medically trained graders. Patients with naevomelanocytic lesions referred to Manchester Royal Eye Hospital and Moorfields Eye Hospital were retrospectively included in this study. All patients underwent imaging tests including optical coherence tomography and ultrasound and management was subsequently decided clinically. Images were anonymised and transferred to the Moorfields Eye Hospital Reading Centre and were reviewed by a trained, masked grader who reached a management decision on the basis of a specific grading protocol. Agreement between decisions made on the basis of clinical examination and imaging ('gold standard') by an expert ophthalmologist in the clinic was compared with the decisions made by a masked ophthalmologist and a masked non-medical grader based on imaging tests alone. There were 102 consecutive patients inclu...Continue Reading

References

May 22, 1998·Archives of Ophthalmology·P SumichJ J Wang
Jan 14, 2004·Archives of Ophthalmology·Sureka ThiagalingamPaul Mitchell
Sep 21, 2004·Cancer Control : Journal of the Moffitt Cancer Center·Curtis E Margo
May 5, 2006·The British Journal of Ophthalmology·I KaisermanJ Pe'er
Sep 10, 2008·Retina·Carol L ShieldsJerry A Shields
Aug 12, 2009·Archives of Ophthalmology·Carol L ShieldsJerry A Shields
Aug 31, 2010·Ophthalmology·Arman MashayekhiJerry A Shields
Feb 3, 2012·Ophthalmology·Sanket U ShahJerry A Shields
May 17, 2013·American Journal of Ophthalmology·Daniele DoroPierangela Cimatti
Jun 22, 2013·JAMA Ophthalmology·Daniel L AlbertusThiran Jayasundera

❮ Previous
Next ❯

Citations

Oct 19, 2017·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Angelica LyMichael Kalloniatis
May 6, 2017·Irish Journal of Medical Science·C BrowneD W Mulvin
Aug 2, 2019·Ocular Oncology and Pathology·Kelsey Roelofs, Ezekiel Weis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical & Experimental Optometry : Journal of the Australian Optometrical Association
Harry Unger
Journal of the Royal Society of Medicine
C J Lyons, J Hungerford
Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
N A BarnardA F Field
© 2021 Meta ULC. All rights reserved