PMID: 2104793Jan 1, 1990Paper

Management of chronic alveolar hypoventilation by nasal ventilation

Chest
J R Bach, A S Alba

Abstract

This is a study of the effect of nocturnal nasal intermittent positive pressure ventilation (NIPPV) on symptoms of chronic alveolar hypoventilation (CAH), sleep oxygen saturation (SaO2), and frequency of hospitalization of patients with progressive neuromuscular respiratory insufficiency or restrictive lung disease from thoracic wall deformity. The nocturnal use of NIPPV is explored in combination with other noninvasive methods of supported ventilation for daytime support as alternatives to tracheostomy and long-term tracheostomy intermittent positive pressure ventilation (TIPPV). Sixteen patients with less than 400 ml of vital capacity (VC) supine and less than 15 minutes of autonomous respiration (free time) maintained a mean SaO2 of 95.9 +/- 2.6 percent (SD) during sleep on NIPPV without added oxygen. Seventeen other patients with adequate free time for a sleep trial unaided had an average SaO2 of 81.8 +/- 11.0 percent which improved to 94.1 +/- 3.4 percent on NIPPV alone. The average length of use of NIPPV by the 42 patients who have used it for one month or more is 21 (3-67) months. All 34 patients who were not dependent on ventilatory support 24 hours a day demonstrated significant improvement and in most cases normalizat...Continue Reading

References

Jul 1, 1988·The American Review of Respiratory Disease·A Mier-JedrzejowiczM Green
Dec 1, 1986·Chest·N S Hill
Apr 1, 1985·Archives of Physical Medicine and Rehabilitation·M L SplaingardG M Harrison
Sep 1, 1953·The American Journal of the Medical Sciences·A L BARACH, G J BECK

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Citations

Jan 22, 2004·Methods in Molecular Medicine·Hans Scheffer
Feb 17, 2001·Current Treatment Options in Neurology·Deborah F. Gelanis
Feb 23, 1991·Lancet
Sep 10, 1994·Lancet·Y RideauA Renardel-Irani
Aug 13, 1998·Critical Care Clinics·S P Keenan, D Brake
Dec 11, 1997·The New England Journal of Medicine·R E Hillberg, D C Johnson
Sep 10, 2005·Journal of Paediatrics and Child Health·Sadasivam SureshDavid Gus M Cooper
Jul 1, 1996·Journal of Neurology, Neurosurgery, and Psychiatry·J M Shneerson
Aug 23, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·Robin S Howard, Craig Davidson
Feb 17, 2001·American Journal of Respiratory and Critical Care Medicine·S Mehta, N S Hill
Apr 25, 2012·The Journal of Spinal Cord Medicine·John R Bach
Apr 1, 2000·American Journal of Physical Medicine & Rehabilitation·J R Bach, S S Chaudhry
Mar 4, 2000·American Journal of Physical Medicine & Rehabilitation·G FerrisJ R Bach
Nov 23, 2006·American Journal of Physical Medicine & Rehabilitation·Tiziana FragassoJohn R Bach
Dec 23, 2009·American Journal of Physical Medicine & Rehabilitation·John R BachAnuradha Patel
Feb 28, 2008·American Journal of Physical Medicine & Rehabilitation·John R BachEugene Komaroff
Jul 22, 2010·American Journal of Physical Medicine & Rehabilitation·John R BachBilal Saulat
Oct 12, 2012·American Journal of Physical Medicine & Rehabilitation·John R BachMarie Eugenia Dominguez
Sep 21, 2013·American Journal of Physical Medicine & Rehabilitation·John Robert BachMiguel Goncalves
May 23, 2008·Pediatric Emergency Care·Jamie N DeisLee Crawley
Nov 25, 2005·Journal of Spinal Disorders & Techniques·John R Bach, Sanjeev Sabharwal
Feb 1, 1995·Chest·J F Masa JiménezF Fuentes Otero

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