Management of chronic hepatitis B and C virus infections

Indian Journal of Pediatrics
Voranush Chongsrisawat, Yong Poovorawan

Abstract

Hepatitis B and C virus (HBV and HCV) infections present an important health problem causing significant morbidity and mortality on a worldwide scale. The younger the subjects infected, the higher the risk predisposing to progression towards chronic infection. Treatment of chronic HBV and HCV infections is aimed at reducing hepatic inflammation and thus improving the symptoms, decreasing the likelihood of long-term sequelae such as hepatocellular carcinoma, and increasing the survival rate. Interferon accelerates the spontaneous course of chronic HBV infection in children with greater disease activity and lower levels of replication. There is limited information on the use of lamivudine and its long-term benefit in children with chronic HBV infection. The response of combination therapy with IFN and ribavirin in children with chronic HCV infection is still under investigation. The long-term clinical and virological effects of various drugs used in chronic HBV and HCV infections on children remain to be evaluated.

References

Apr 10, 1975·The New England Journal of Medicine·C E StevensW C Lee
Oct 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M Ruiz-MorenoV Carreño
Jun 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M Ruiz-MorenoV Carreño
Sep 1, 1981·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R G KnodellJ Wollman
Dec 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F BortolottiA Bertolini
Oct 1, 1995·The Journal of Pediatrics·T FujisawaM Onoue
Nov 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G FattovichW F Carman
Apr 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·K C Hyams
Aug 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C BarberaT Parrella
Feb 1, 1996·Archives of Disease in Childhood·R IorioA Vegnente
Sep 20, 1997·European Journal of Pediatrics·S MatsuokaY Kuroda
Apr 16, 1998·The Pediatric Infectious Disease Journal·M M JonasA R Perez-Atayde
Jun 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M I AllenL D Condreay
Jul 9, 1998·The New England Journal of Medicine·C L LaiD F Gray
Mar 3, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N C TassopoulosD F Gray
Mar 3, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S M LinY F Liaw
Apr 24, 1999·Intervirology·A R ZanettiN Principi
Aug 6, 1999·Journal of Pediatric Gastroenterology and Nutrition·P Jara, F Bortolotti
Feb 26, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N KoçakF Gürakan
Apr 5, 2000·Journal of Pediatric Gastroenterology and Nutrition·L ZancanE S d'Amore
Aug 12, 2000·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
Oct 29, 2000·The American Journal of Gastroenterology·N KoçakA Yüce
Feb 15, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K R ReddyJ DePamphilis

❮ Previous
Next ❯

Citations

May 8, 2003·Current Gastroenterology Reports·Kathleen B Schwarz
Mar 17, 2004·BMC Gastroenterology·Yildiz PeksenAhmet Tevfik Sunter

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.