Management of complications of Mycobacterium ulcerans disease: A three-year review

International Journal of Mycobacteriology
Emmanuel J K Adu

Abstract

Infection with Mycobacterium ulcerans (MU) causes extensive destruction of tissues with the formation of large ulcers on exposed parts of the body. Healing leads to extensive scarring and other complications which may impair function. To document the complications of MU disease and the reconstructive surgery performed to correct them. Prospective from January 2010 to December 2012. Ahafo Ano, Amansie West, Asunafo, and Upper Denkyira districts of Ghana. Patients with unhealed lesions after completing 8weeks of rifampicin and streptomycin treatment, and patients with complications of MU disease were selected and prepared for surgical treatment. 61 patients were treated successfully with rifampicin and streptomycin without complications. 65 patients presented with complications; they comprised 34 males and 31 females. Their ages ranged from 1year 3months to 80years with mean age of 29.7 (S.D. 20.1). The types of lesions seen were ulcers (54), contractures (7), chronic osteomyelitis (one), subluxation of knee joint (one), salivary gland fistula (one) and Marjolin's ulcer (one). The lesions were distributed as follows: 69.2% on the lower, and 23.1% on the upper limbs, 6.2% on the head and neck and 1.5% on the trunk. Wound excision ...Continue Reading

References

Mar 1, 1988·The Journal of Infectious Diseases·M PimslerW M Meyers
Mar 19, 2002·Emerging Infectious Diseases·George AmofahJonathan Addy
Jan 23, 2004·Proceedings of the National Academy of Sciences of the United States of America·Timothy P StinearStewart T Cole

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Citations

Mar 15, 2016·International Journal of Mycobacteriology·Emmanuel J K Adu, Edwin Ampadu
Jan 19, 2018·Journal of Clinical Microbiology·Jeannette Guarner
Aug 24, 2018·The Cochrane Database of Systematic Reviews·Rie R YotsuNorihisa Ishii

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