Abstract
Since co-morbid depression can complicate medical conditions such as cardiovascular disease and cancer, physicians may treat depression more aggressively in patients with these conditions. This study compared antidepressant medication use in persons with and without medical co-morbidities. This cross-sectional study was conducted in a national network of outpatient electronic medical record users. Participants included active adult patients with an active diagnosis of depression as of 11/30/05 (the "prevalent" population, 185,029 patients) or a new episode of depression during the one-year period 12/1/03-11/30/04 (the "incident" population, 29,768 patients). For each population, four co-morbid conditions were defined--diabetes, coronary heart disease (CHD), stroke, and cancer. Prescription of antidepressant medication was compared for persons with and without each medical condition. The most common medical condition was diabetes, with cancer being the least common (7.6% and 2.4% of the prevalent population). Overall, 69.6% of the prevalent population and 76.1% of the incident population were treated with antidepressant medications. For the prevalent population, treatment was significantly more likely for patients with diabetes ...Continue Reading
References
Oct 1, 1993·Archives of Family Medicine·D S MainR S Miller
Feb 5, 1998·JAMA : the Journal of the American Medical Association·S P RooseI Gergel
Feb 7, 1993·Quality in Health Care : QHC·N FreemantleA F Long
Jul 7, 1999·The Milbank Quarterly·J UnützerJ Miranda
Jun 2, 2000·Diabetes Care·P J LustmanR E Clouse
Mar 10, 2001·Stroke; a Journal of Cerebral Circulation·A HouseA Vail
Sep 15, 2001·Journal of General Internal Medicine·S M MavigliaD W Bates
Mar 5, 2002·Diabetes Care·Leonard E EgedeKit Simpson
Aug 10, 2002·JAMA : the Journal of the American Medical Association·Alexander H GlassmanUNKNOWN Sertraline Antidepressant Heart Attack Randomized Trial (SADHEART) Group
Dec 11, 2002·JAMA : the Journal of the American Medical Association·Jürgen UnützerUNKNOWN IMPACT Investigators. Improving Mood-Promoting Access to Collaborative Treatment
Jan 4, 2003·Stroke; a Journal of Cerebral Circulation·N B Lincoln, T Flannaghan
Jun 19, 2003·JAMA : the Journal of the American Medical Association·Ronald C KesslerUNKNOWN National Comorbidity Survey Replication
Sep 30, 2003·The American Journal of Psychiatry·Ricardo E JorgeSergio Starkstein
Nov 5, 2003·Palliative Medicine·H A Martine MeyerPaul T Seed
Apr 17, 2004·Journal of the American Geriatrics Society·Ellen M WhyteMary Ganguli
Jun 16, 2004·Annals of Internal Medicine·John W WilliamsUNKNOWN IMPACT Investigators
Jul 21, 2004·Journal of the National Cancer Institute. Monographs·Mary Jane Massie
May 28, 2005·Diabetes Care·Leonard E EgedeDeyi Zheng
Jul 6, 2005·Archives of General Psychiatry·C Barr TaylorUNKNOWN ENRICHD Investigators
Sep 24, 2005·Stroke; a Journal of Cerebral Circulation·Maree L Hackett, Craig S Anderson
Jan 25, 2007·JAMA : the Journal of the American Medical Association·François LespéranceUNKNOWN CREATE Investigators
Citations
Jan 19, 2011·Annals of Family Medicine·James M GillMichael I Lieberman
Sep 7, 2014·Family Practice·Lucy DoosUmesh T Kadam
Feb 14, 2015·Journal of Psychosomatic Research·Matthew MenearLouise Fournier
Feb 5, 2015·Journal of Psychosomatic Research·Matthew MenearLouise Fournier
Apr 26, 2011·International Journal of Medical Informatics·Nhi-Ha T TrinhAlbert Yeung
Jan 11, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Elke JeschkeHarald Matthes
Jan 3, 2013·Primary Care Diabetes·Norbert HermannsFrank Snoek
Nov 26, 2009·Journal of Adolescence·Zeynep Tanes, Zeynep Cemalcilar
Sep 13, 2011·American Journal on Intellectual and Developmental Disabilities·Carl V TylerAnil K Jain
Dec 13, 2012·Diabetologia·F HeF X Huang
Sep 21, 2013·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Nur Islami Mohd Fahmi TengWan Zurinah Wan Ngah
Feb 25, 2014·Medical Care·Neil JordanTodd A Lee