Management of focal chondral lesion in the knee joint.

Knee Surgery & Related Research
Seung-Suk SeoDae-Won Jung

Abstract

Articular cartilage does not contain vascular, nervous and lymphatic tissue and chondrocytes hardly participate in the healing or repair process of chondral tissue because of being surrounded by plenty of extracellular matrix. Therefore, the injury to articular cartilage frequently requires an operative treatment. The goal of surgical repair of articular cartilage is to regenerate nearly normal chondral tissue and prevent degenerative arthritis caused by the articular cartilage defect. Microfracture is a kind of cartilage repair procedure that makes a fibrin clot containing mesenchymal stem cells in the chondral lesion. Microfracture is a simple procedure but it has a disadvantage that the repaired tissue is fibrocartilage. Autologous chondrocyte implantation has an advantage that it implants fully differentiated chondrocytes to the lesion, which theoretically produces hyaline cartilage. Its disadvantages are that it is a two stage and a costly procedure. Osteochondral autograft transplantation is a one stage procedure and repairs the lesion with hyaline cartilage. But its limitation is the lack of donor site availability. Surgeons who understand the theoretical background, indications, surgical methods, rehabilitation, complic...Continue Reading

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Citations

Jan 15, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·P VolpiL de Girolamo
Apr 1, 2014·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Deepak GoyalArash Sharafat Vaziri
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Aug 25, 2020·Cartilage·Wenqiang YanDongquan Shi
Feb 23, 2020·Biochemistry Research International·Xiangbo MengXinluan Wang
Sep 11, 2021·The Journal of Knee Surgery·Jorge ChahlaJack Farr

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Methods Mentioned

BETA
lavage
biopsy

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