Management of hydrocephalus in pediatric metastatic tumors of the posterior fossa at presentation

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Luc Le FournierLaurent Riffaud

Abstract

Presence of metastases in newly diagnosed pediatric posterior fossa tumors (PFT) is not a rare situation, but optimal treatment of associated hydrocephalus in these children has remained undetermined. Twenty-nine children treated between January 2005 and December 2015 for a metastatic PFT associated with hydrocephalus constituted the study cohort. Patients were divided into three groups: ventriculoperitoneal shunt (VPS), endoscopic third ventriculostomy (ETV), and temporary ventricular drainage before or during tumor resection (PVD). There were 4 VPS, 18 ETV, and 7 PVD. The global incidence of CSF diversion failure was 52%. No case of dysfunction or dissemination of metastatic cells occurred in the VPS group. Recurrence of hydrocephalus occurred in 55% of the ETV group. Presence of multiple macroscopic metastases and CSF metastatic cells after tumor surgery was associated with ETV failure. Fifty-seven percent of the children in the PVD group were reoperated after an average time of 53 days. Specific oncologic treatment was initiated earlier in the VPS group (11 days) compared to ETV (27 days) and PVD (23 days) groups. ETV should be avoided in cases of multiple macroscopic metastases, and children who underwent ETV must be follo...Continue Reading

References

Jan 1, 1977·Journal of Neurosurgery·L Albright, D H Reigel
May 1, 1976·Journal of Neurosurgery·H J HoffmanR P Humphreys
Feb 6, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Edgardo SchijmanTai Tong Wong
Jun 29, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Claudio RuggieroGiuseppe Maggi
Nov 8, 2005·Journal of Neurosurgery·Jacques GrillChristian Sainte-Rose
Sep 8, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J VerlooyF Doz
Oct 3, 2006·The Lancet Oncology·Jacques GrillChantal Kalifa
Oct 21, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·C Di RoccoG Tamburrini
Jan 18, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sandrine de RibaupierreJ-G Villemure
Mar 6, 2007·Pediatric Neurosurgery·Bernt Johan Due-Tønnessen, Eirik Helseth
Jul 24, 2007·The Lancet Oncology·Richard G GrundyUNKNOWN Children's Cancer and Leukaemia Group (formerly UKCCSG) Brain Tumour Committee
Jun 3, 2008·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ricardo Santos de OliveiraHélio Rubens Machado
Sep 25, 2008·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·G TamburriniC Di Rocco
Apr 18, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Thomas E Merchant
May 5, 2009·Journal of Neurosurgery. Pediatrics·Jay Riva-CambrinJames M Drake
Aug 26, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nasser M F El-Ghandour
Jun 3, 2011·Journal of Neurosurgery. Pediatrics·Triantafyllos Bouras, Spyros Sgouros
Nov 26, 2011·Acta Neurochirurgica. Supplement·Triantafyllos Bouras, Spyros Sgouros
Mar 3, 2012·World Neurosurgery·Federico Di RoccoChristian Sainte-Rose
Dec 20, 2014·Journal of Neurosurgery. Pediatrics·Christian SchneiderMichael D Taylor
Aug 4, 2015·Surgical Neurology International·Sandi LamAndrew Jea
Sep 10, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Chih-Ta Lin, Jay K Riva-Cambrin
Feb 13, 2016·Journal of Neurosurgery. Pediatrics·Matthew G StovellConor L Mallucci

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Mar 22, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Fabio FrisoliShih-Shan Lang

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