We used the discharge database of the University Hospital Consortium to determine the management and early outcome of neonates with hypoplastic left heart syndrome admitted to member institutions from 1990 to 1999. Of the 2,264 patients, 1,203 underwent a Norwood procedure, with 42% mortality. Cardiac transplantation was performed in 72, with 38% mortality, and 217 (10%) were discharged without any surgical procedure. The proportion of patients managed by the Norwood procedure increased from 43% during the first half of the decade to 59% in the second half, with corresponding decreases in the proportion managed by transplantation or nonintervention. A mortality rate of < or =40% was achieved in all 5 institutions performing >50 Norwood procedures, and by 9 of 40 institutions performing <50. Performance of a Norwood procedure has become the most frequent management for neonates with hypoplastic left heart syndrome. Lower operative mortality rates are generally, but not exclusively, achieved by institutions with high surgical volume.
Ten-year institutional experience with palliative surgery for hypoplastic left heart syndrome. Risk factors related to stage I mortality
Discordance of databases designed for claims payment versus clinical information systems. Implications for outcomes research
Intermediate survival in neonates with aortic atresia: a multi-institutional study. The Congenital Heart Surgeons Society
The modified Norwood procedure for hypoplastic left heart syndrome: early to intermediate results of 120 patients with particular reference to aortic arch repair
The association between hospital volume and survival after acute myocardial infarction in elderly patients
Can cardiovascular clinical characteristics be identified and outcome models be developed from an in-patient claims database?
Results after Norwood procedure and subsequent cavopulmonary anastomoses for typical hypoplastic left heart syndrome and similar complex cardiovascular malformations
Survival analysis and risk factors for mortality in transplantation and staged surgery for hypoplastic left heart syndrome
Survival after reconstructive surgery for hypoplastic left heart syndrome: A 15-year experience from a single institution
Mortality associated with congenital heart defects in the United States: trends and racial disparities, 1979-1997
The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart disease
Cardiovascular magnetic resonance of pulmonary artery growth and ventricular function after Norwood procedure with Sano modification
Choices doctors would make if their infant had hypoplastic left heart syndrome: comparison of survey data from 1999 and 2007
Evolution of treatment options and outcomes for hypoplastic left heart syndrome over an 18-year period
Outcomes of surgical treatment of infants with hypoplastic left heart syndrome: an institutional experience 1983-2004
Use of an administrative database to determine clinical management and outcomes in congenital heart disease
Risk-stratified approach to hybrid transcatheter-surgical palliation of hypoplastic left heart syndrome
Patient-Specific Multi-Scale Model Analysis of Hemodynamics Following the Hybrid Norwood Procedure for Hypoplastic Left Heart Syndrome: Effects of Reverse Blalock-Taussig Shunt Diameter
Cardiovascular Diseases: Risk Factors
Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.