Management of Intracranial Hemorrhage in the Anticoagulated Patient

Neurosurgery Clinics of North America
R Loch Macdonald

Abstract

Antiplatelet and anticoagulant drugs (antithrombotic drugs) can cause or be associated with intracranial hemorrhage. Patients who take antithrombotic drugs are at higher risk for intracranial hemorrhage after trauma and are neurologically worse acutely compared with patients not on antithrombotic drugs. Treatment of patients on antithrombotic drugs who have intracranial hemorrhage includes reversal of anticoagulant drugs in almost all cases. This article is a synopsis of the data pertaining to intracranial hemorrhage and antithrombotic drugs and methods to diagnose the pharmacologic effects and to reverse the effects of these drugs in patients with traumatic or spontaneous intracranial hemorrhage.

Citations

Oct 14, 2019·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Liming QiuNicolas Kon Kam King
Nov 25, 2020·The American Journal of Emergency Medicine·Benjamin TraversDavid Donaldson

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