Management of isolated optic neuritis in France: survey of neurologists and ophthalmologists

Revue neurologique
Olivier CalvettiValérie Biousse

Abstract

Acute isolated optic neuritis is often the first manifestation of multiple sclerosis (MS). Despite the results of several clinical trials its management remains controversial. With the advent of new disease-modifying agents for the treatment of MS, management of isolated optic neuritis has become more complicated. The goal of this study was to evaluate the current clinical practice of French ophthalmologists and neurologists in the management of acute isolated optic neuritis, and to evaluate the impact of recently published randomized clinical trials on their practice. A survey, including 24 questions on the diagnosis and treatment of acute isolated optic neuritis was sent to all neurologists and to a sample of ophthalmologists in France. The responses of 655 neurologists and 141 ophthalmologists were analyzed. This study shows mostly that patients initially present more frequently to ophthalmologists, and are subsequently referred to neurologists. Most optic neuritis patients undergo a brain MRI and a lumbar puncture. Although most patients receive high dose intravenous steroids, up to 15% of neurologists and 21% of ophthalmologists still recommend oral prednisone (1 mg/kg per day). Steroids are often prescribed for the wrong ...Continue Reading

References

Jul 29, 2000·Australian and New Zealand Journal of Medicine·I ScottP Fairweather
May 30, 2001·Lancet·G ComiUNKNOWN Early Treatment of Multiple Sclerosis Study Group
May 6, 2003·Annals of Neurology·Catherine M DaltonDavid H Miller
Sep 10, 2003·Neurology·E M FrohmanUNKNOWN Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Dec 4, 2003·International Journal of Medical Informatics·Neset Hikmet, Shaw K Chen
Sep 21, 2004·Journal of Neurology·Xavier Montalban
Nov 12, 2005·Annals of Neurology·Chris H PolmanJerry S Wolinsky
Apr 12, 2006·Archives of Neurology·Sean J PittockMoses Rodriguez

❮ Previous
Next ❯

Citations

Dec 22, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Amber R SalterRuth Ann Marrie
Apr 19, 2018·Asia-Pacific Journal of Ophthalmology·Ethan Meltzer, Sashank Prasad

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
Edward J AtkinsValérie Biousse
Journal of the Neurological Sciences
Valérie BiousseOptic Neuritis Survey Group
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
Rune MidgardKjell-Morten Myhr
Multiple Sclerosis : Clinical and Laboratory Research
Mark S FreedmanParis Workshop Group
© 2022 Meta ULC. All rights reserved