Management of low-output pancreatic fistulas with fibrin glue

American Journal of Surgery
C Clay CothrenGregory V Stiegmann

Abstract

Despite advances in surgical, endoscopic, and percutaneous therapeutic techniques, pancreatic fistulas remain a source of significant morbidity and long-term patient discomfort. The intraoperative use of fibrin sealant has been used prophylactically to prevent formation of fistula. We recognized the potential use of fibrin glue as a therapeutic modality for successful resolution of low-output pancreatic fistulas. Three patients with low (<20 ml per day) output pancreatic fistulas underwent fluoroscopically directed injection of fibrin glue along their fistula tract. All 3 patients underwent successful fibrin glue injection without procedural complication. All fistula output stopped, and the 3 patients remained asymptomatic at 1 year. Fibrin glue inserted with image-guided catheter delivery systems may be a useful option in selected patients with low-output pancreatic fistulas.

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Citations

Apr 1, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·David Mahvi
May 2, 2013·The Surgical Clinics of North America·Jeffrey A Blatnik, Jeffrey M Hardacre
Oct 24, 2007·Surgery·Rajalakshmi R NairSyed A Ahmad
Mar 31, 2006·Journal of the American College of Surgeons·David M Albala, Jeffrey H Lawson
Jun 17, 2010·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Sidney Johnson, Justin James Clark
Jun 24, 2008·Gastroenterología y hepatología·Salvador NavarroUNKNOWN Club Español Biliopancreático para el Tratamiento de la Pancreatitis Aguda

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