Management of microcalcifications that develop at the lumpectomy site after breast-conserving therapy

Radiology
S A VoraM J Homer

Abstract

To design a decision tree according to time from irradiation and site, morphology, and number of microcalcifications for the rational treatment of patients with microcalcifications at the lumpectomy site after breast-conserving therapy (BCT), to minimize performance of biopsy. From a database of 504 women selected to receive BCT, those developing probably benign microcalcifications within 3 years of BCT received close follow-up with mammography. Patients developing fewer than four probably benign microcalcifications more than 3 years after treatment were offered mammography or biopsy. If microcalcifications appeared malignant or patients developed four or more microcalcifications after 3 years, biopsy was performed. Twenty-eight patients (29 breasts [5.7%]) developed microcalcifications confined to the lumpectomy site. Fifteen patients (15 breasts) developed microcalcifications within 3 years of BCT and were followed up with mammography. Thirteen patients (14 breasts) developed microcalcifications confined to the lumpectomy site after more than 3 years. Among the latter group, microcalcifications appeared malignant in four breasts, and biopsy specimens revealed three recurrences. The remaining 10 breasts were followed up with m...Continue Reading

Citations

Jun 17, 2009·American Journal of Clinical Oncology·Heather E NewlinNancy P Mendenhall
Jan 24, 2007·AJR. American Journal of Roentgenology·Işil Günhan-Bilgen, Ayşenur Oktay
Apr 15, 2008·International Journal of Radiation Oncology, Biology, Physics·Kevin LinLawrence W Bassett
Jul 16, 2002·Radiologic Clinics of North America·D David Dershaw
Nov 17, 2009·The Breast : Official Journal of the European Society of Mastology·M RuchK Wasser

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