Management of neonatal thrombosis

Clinics in Perinatology
Matthew A Saxonhouse

Abstract

Neonates have one of the highest risks for thromboembolism among pediatric patients. This risk is attributable to a combination of multiple genetic and acquired risk factors. Despite a significant number of these events being either life threatening or limb threatening, there is limited evidence on appropriate management strategy. Most of what is recommended is based on uncontrolled studies, case series, or expert opinion. This review begins with a discussion of the neonatal hemostatic system, focusing on the common sites and imaging modalities for the detection of neonatal thrombosis. Perinatal and postnatal risk factors are presented and management options discussed.

References

Sep 14, 1978·The New England Journal of Medicine·S T MokrohiskyM A Simmons
May 1, 1991·Journal of Pediatric Surgery·C Le CoultreD C Belli
Jan 1, 1990·The American Journal of Pediatric Hematology/oncology·M AndrewM Johnston
Nov 1, 1989·Plastic and Reconstructive Surgery·K A Denkler, B E Cohen
Apr 1, 1996·Annals of Hematology·B DahlbäckB Zöller
Apr 23, 1997·JAMA : the Journal of the American Medical Association·P M RidkerJ E Buring
May 1, 1997·Archives of Disease in Childhood. Fetal and Neonatal Edition·U Nowak-GöttlU Göbel
Feb 13, 2001·Blood·U Nowak-GöttlUNKNOWN Childhood Thrombophilia Study Group
Aug 11, 2001·The New England Journal of Medicine·G deVeberUNKNOWN Canadian Pediatric Ischemic Stroke Study Group
Nov 20, 2001·The Journal of Pediatrics·C H van OmmenM Peters
Jan 5, 2002·Journal of Perinatology : Official Journal of the California Perinatal Association·M Varughese, T H Koh
Feb 28, 2002·Archives of Disease in Childhood·C BarnesP Monagle
Jun 26, 2002·Journal of Perinatology : Official Journal of the California Perinatal Association·Mariana C BasergaAugusto Sola
Aug 24, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·D W Cartwright
Mar 28, 2003·American Journal of Perinatology·M J Torres-ValdiviesoF Gutiérrez
May 22, 2003·Journal of Pediatric Hematology/oncology·Michael WangUNKNOWN Pediatric Coagulation Consortium
Aug 26, 2003·Archives of Disease in Childhood. Fetal and Neonatal Edition·W StreifM P Massicotte
Aug 27, 2003·Circulation·Christine HellerUNKNOWN Childhood Stroke Study Group
Mar 11, 2004·Blood Reviews·A GreenwayP Monagle
Apr 8, 2004·The Journal of Pediatrics·Laila ObaidPo-Yin Cheung
Oct 23, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·D W Cartwright
Nov 6, 2004·Journal of Child Neurology·Meredith R GolombGabrielle A deVeber
Feb 5, 2005·Pathophysiology of Haemostasis and Thrombosis·Ulrike Nowak-GöttlRonald Sträter
Feb 9, 2005·Brain : a Journal of Neurology·G SébireF J Kirkham
Feb 11, 2005·JAMA : the Journal of the American Medical Association·Janet LeeYvonne W Wu
Jun 24, 2005·The Journal of Pediatrics·Stephen D MarksVibhuti S Shah
Jul 27, 2005·British Journal of Haematology·Elizabeth A Chalmers
Aug 16, 2005·Blood·Marilyn J Manco-Johnson
Nov 11, 2005·Neonatal Network : NN·Julie Martchenke, Lynn Boshkov
Nov 24, 2005·Hematology·Frits R Rosendaal
Dec 13, 2005·Seminars in Neurology·Yvonne W WuKarin B Nelson
Mar 8, 2006·Seminars in Fetal & Neonatal Medicine·Courtney Thornburg, Steven Pipe
Mar 15, 2006·Archives of Neurology·Karima C FitzgeraldMeredith R Golomb
Apr 28, 2006·Plastic and Reconstructive Surgery·Christopher J CoombsPaul Monagle
May 9, 2006·Journal of Pediatric Hematology/oncology·Ibrahim CanerRahmi Ors
May 20, 2006·Thrombosis Research·Rod W Hunt, Terrie E Inder
Aug 1, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·D Kenny, B Tsai-Goodman

❮ Previous
Next ❯

Citations

Nov 11, 2015·Seminars in Fetal & Neonatal Medicine·Revathi RajagopalPaul Monagle
Oct 12, 2013·The Journal of Pediatrics·Habib HaddadWalid El-Naggar
Jan 20, 2015·British Journal of Haematology·Andrew Will
Aug 8, 2015·Clinics in Perinatology·Matthew A Saxonhouse
May 17, 2014·Seminars in Arthritis and Rheumatism·Oren GordonShoshana Revel Vilk
Mar 29, 2014·Cardiology in the Young·Keiichi FujiwaraHisanori Sakazaki
Nov 8, 2016·The Cochrane Database of Systematic Reviews·Olga RomantsikMaria Grazia Calevo
May 4, 2021·Journal of Neonatal-perinatal Medicine·N ImadF M R Maoulainine
Nov 3, 2021·Journal of Clinical Pharmacy and Therapeutics·Süleyman Bayraktar, Bilge Tanyeri-Bayraktar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antianginal Drugs: Mechanisms of Action

Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Journal of Perinatology : Official Journal of the California Perinatal Association
Matthew A Saxonhouse, D J Burchfield
International Journal of Pediatrics
H A van ElterenE Lopriore
Pediatric Cardiology
Edgard A BendalyRoger A Hurwitz
© 2022 Meta ULC. All rights reserved