Management of nephrolithiasis in autosomal dominant polycystic kidney disease - A single center experience.

Urology Annals
Ramen BaishyaMahesh R Desai

Abstract

To evaluate available options for the management of nephrolithiasis in patients with autosomal dominant polycystic kidney disease (ADPKD). Case files of all the patients with ADPKD treated in our hospital in the last 18 years were evaluated. Their demographic details, clinical presentations, investigations, treatments, and outcomes were critically analyzed. There were a total of 19 patients (23 renal units) with nephrolithiasis among 452 consecutive cases of ADPKD. Male-to-female ratio was 3.75:1. The mean age of the patients was 43.3 years (range 23 to 60 years). The most common presentations were pain and hematuria (27.7% each). Mean serum creatinine was 7.2 mg/ dl (range 0.8-18.1 mg/dl) at presentation. The mean stone size was 115 mm(2) (range 36 to 980 mm(2)). The majority of the stones were calyceal (n = 10). Ten renal units (nine patients) required intervention, while the rest were treated conservatively. Treatment offered included open nephrectomy for non-functioning infected kidney (n = 1), extracorporeal shock wave lithotripsy (ESWL, n = 3), ureterorenoscopy (URS, n = 3), and percutaneous nephrolithotomy (PCNL, n = 3). All patients undergoing URS and PCNL had complete clearance, while those undergoing ESWL had a residu...Continue Reading

References

Apr 1, 1988·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·V E TorresJ W Segura
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Citations

Aug 29, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Niek F CasteleijnUNKNOWN DIPAK Consortium
Nov 24, 2017·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Jacob W Potts, Shaker A Mousa
Mar 9, 2017·World Journal of Urology·Mordechai DuvdevaniHassan Razvi
Aug 6, 2020·Canadian Journal of Kidney Health and Disease·Vinusha KalatharanAmit X Garg
Dec 8, 2020·Canadian Journal of Kidney Health and Disease·Vinusha KalatharanAmit X Garg
Jun 9, 2016·Open Access Macedonian Journal of Medical Sciences·Valbona BajramiMyftar Barbullushi

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Methods Mentioned

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