Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis; An Evidence-based Consensus Guideline from ECCO and ESPGHAN

Journal of Pediatric Gastroenterology and Nutrition
Dan TurnerR K Russell

Abstract

Acute severe colitis (ASC) is one of the few emergencies in paediatric gastroenterology. Tight monitoring and timely medical and surgical interventions may improve outcomes and minimize morbidity and mortality. We aimed to standardize daily treatment of ASC in children through detailed recommendations and practice points which are based on a systematic review of the literature and consensus of experts. These guidelines are a joint effort of the European Crohn's and Colitis Organization (ECCO) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). Fifteen predefined questions were addressed by working subgroups. An iterative consensus process, including two face-to-face meetings, was followed by voting by the national representatives of ECCO and all members of the Paediatric Inflammatory Bowel Disease (IBD) Porto group of ESPGHAN (43 voting experts). A total of 24 recommendations and 43 practice points were endorsed with a consensus rate of at least 91% regarding diagnosis, monitoring and management of ASC in children. A summary flowchart is presented based on daily scoring of the Paediatric Ulcerative Colitis Activity Index (PUCAI). Several topics have been altered since the previous 2011 g...Continue Reading

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Citations

Mar 9, 2019·Current Pharmaceutical Design·Dan Turner
Jan 22, 2019·Journal of Pediatric Gastroenterology and Nutrition·Jiri BronskyAlmuthe Christina Hauer
Jun 3, 2020·The Annals of Pharmacotherapy·Shannon IngletWhitney Mortensen
Mar 7, 2020·Journal of Pediatric Gastroenterology and Nutrition·Isabel Pinto PaisJorge Amil Dias
May 28, 2020·Journal of Pediatric Gastroenterology and Nutrition·Ewa StawowczykMałgorzata Mossakowska
Feb 19, 2019·Frontiers in Pediatrics·Rafael Martín-MasotVictor Manuel Navas-López
Aug 28, 2019·Intestinal research·Tadahiro YanagiToshiaki Shimizu
Feb 27, 2020·Journal of Pediatric Gastroenterology and Nutrition·Luca ScaralloPaolo Lionetti
Sep 22, 2020·Pediatric Gastroenterology, Hepatology & Nutrition·Katsuhiro Arai
Jul 19, 2019·United European Gastroenterology Journal·Matteo BramuzzoUNKNOWN SIGENP IBD Working Group
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Jan 24, 2019·International Journal of Molecular Sciences·Giovanna FerraraRolando Cimaz
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Feb 6, 2021·Journal of Clinical Pharmacy and Therapeutics·Xiao WangDa-Li Sun
Jan 29, 2021·Pediatric Gastroenterology, Hepatology & Nutrition·Hirotaka ShimizuToshiaki Shimizu

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