Management of penetrating intraperitoneal colon injuries: A meta-analysis and practice management guideline from the Eastern Association for the Surgery of Trauma

The Journal of Trauma and Acute Care Surgery
Daniel C CullinaneBryce Robinson

Abstract

The management of penetrating colon injuries in civilians has evolved over the last four decades. The objectives of this meta-analysis are to evaluate the current treatment regimens available for penetrating colon injuries and assess the role of anastomosis in damage control surgery to develop a practice management guideline for surgeons. Using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology, a subcommittee of the Practice Management Guidelines section of EAST conducted a systematic review using MEDLINE and EMBASE articles from 1980 through 2017. We developed three relevant problem, intervention, comparison, and outcome (PICO) questions regarding penetrating colon injuries. Outcomes of interest included mortality and infectious abdominal complications. Thirty-seven studies were identified for analysis, of which 16 met criteria for quantitative meta-analysis and included 705 patients considered low-risk in six prospective randomized studies. Seven hundred thirty-eight patients in 10 studies undergoing damage control laparotomy and repair or resection and anastomosis (R&A) were included in a separate meta-analysis. Meta-analysis of high-risk patients undergoing repair or R&A was not feas...Continue Reading

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Citations

Sep 19, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Svenja SliwinskiPa Tri Zia Malkomes
Feb 23, 2021·The Journal of Trauma and Acute Care Surgery·Zain G HashmiAdil H Haider
Jun 1, 2021·ANZ Journal of Surgery·George OosthuizenDamian Clarke
Sep 1, 2020·The Journal of Surgical Research·Joseph D BozzayUNKNOWN Infectious Disease Clinical Research Program Trauma Infectious Disease Outcomes Study Group
Sep 10, 2021·BMC Surgery·Camille TantardiniNathalie Chereau
Sep 30, 2021·World Journal of Surgery·G V OosthuizenD L Clarke

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