Management of perivascular epithelioid cell tumor of the liver: A case report and review of the literature

Oncology Letters
Daren LiuLiping Cao

Abstract

Perivascular epithelioid cell tumor (PEComa) is a rare tumor that originates from mesenchymal tissues. Cases of PEComa in the liver are extremely rare. The present study aimed to analyze the clinical features of PEComa in the liver and discuss its management. Here we report a 25-year-old female with multiple lesions of low density with poorly defined borders in the liver, as shown by a computed tomography (CT) scan. A partial hepatectomy was proceeded and PEComa was diagnosed by immunohistochemistry. No evidence of recurrence was observed during the one year follow-up. A total of 20 patients with hepatic PEComa, including one case from the present study and 19 cases that were reported in literature between June 2001 and December 2012, were reviewed and analyzed. The mean patient age was 43.4 years (range, 25-67 years) and the cases consisted of 18 female and two male patients. The tumor size ranged between 2.0×1.6 and 15.0×12.0 cm. Of the 20 patients, nine were asymptomatic and 11 had mild to significant complaints. Immunohistochemistry plays a key role in the diagnosis of PEComa. All the cases in this study were strongly positive for human melanoma black-45. A surgical resection is the gold standard for curative intent. All th...Continue Reading

References

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Citations

Jan 8, 2014·World Journal of Surgical Oncology·Moritz WildgruberJochen Gaa
Jan 15, 2014·World Journal of Surgical Oncology·Amane KanazawaChikara Kunisaki
Apr 25, 2019·Journal of Cellular Biochemistry·Wenbo HuFei Li
May 9, 2015·World Journal of Gastroenterology : WJG·Toshiya MaebayashiMasahiko Sugitani

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Methods Mentioned

BETA
SMA
surgical resection

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