Management of Restless Legs Syndrome/Willis-Ekbom Disease in Hospitalized and Perioperative Patients

Sleep Medicine Clinics
Cathy Goldstein

Abstract

Restless legs syndrome (RLS) is a sensorimotor disorder that can cause significant discomfort, impaired quality of life, poor mood, and disturbed sleep. Because the disorder is chronic and associated with multiple comorbidities, RLS can be seen in an inpatient or perioperative setting. Certain characteristics of the hospitalized or surgical context can exacerbate or unmask RLS. Importantly, RLS and the associated discomfort and insomnia can prolong hospital stay and negatively impact outcomes. RLS medications should be continued during the hospital admission when possible. Avoidance of excessive phlebotomy and medications known to trigger RLS is helpful. Patients should increase activity when acceptable.

References

Jan 1, 1987·Neuropsychobiology·P LehmkuhlI Pichlmayr
Oct 1, 1987·Anesthesia and Analgesia·S WatanabeH Naito
Feb 1, 1987·Southern Medical Journal·Y K Shin
Jan 1, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·J MontplaisirP Lespérance
Feb 20, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·V Collado-SeidelC Trenkwalder
Sep 28, 1999·Annals of Emergency Medicine·D L Drotts, D R Vinson
Feb 9, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Martin MichaudJacques Montplaisir
Apr 1, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jiro TakakiTomifusa Kuboki
Apr 30, 2003·The Journal of Physiology·Sat Bir S KhalsaCharles A Czeisler
Aug 2, 2003·Nature Reviews. Neuroscience·Michael H HastingsElizabeth S Maywood
Oct 29, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·T-Christian H MixAllan J Collins
Mar 3, 2004·Annals of Neurology·Martin MichaudJacques Montplaisir
Mar 26, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·James A SloandRebeca D Monk
Apr 28, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·David KavanaghColin C Geddes
May 29, 2004·Sleep Medicine·Gian Luigi GigliRiccardo Budai
Oct 30, 2004·Sleep Medicine·Isabelle RaymondManon Choinière
Apr 28, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·George R BailiePeter L Lane
Sep 5, 2006·Journal of the American Board of Family Medicine : JABFM·Melissa McManama AukermanBeth Bailey
Jan 4, 2007·Advances in Chronic Kidney Disease·Fliss E M MurtaghIrene J Higginson
Dec 18, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Wayne A HeningRobert Yoakum
Feb 29, 2008·The Journal of Neuropsychiatry and Clinical Neurosciences·Hochang B LeeConstantine G Lyketsos
Jun 20, 2008·Journal of Gerontological Nursing·Kathy Missildine
Oct 7, 2008·Blood Reviews·Mary Ann KnovichFrank M Torti
Nov 21, 2008·The New England Journal of Medicine·Thomas A CrozierSvenja Happe
Aug 18, 2009·Journal of the American Geriatrics Society·Cynthia J BrownRichard M Allman
Sep 15, 2009·Journal of Circadian Rhythms·Akbar SharifianAli Fardi
Jan 2, 2010·Archives of Gerontology and Geriatrics·Sibel EyigorRuchan Uslu
Feb 5, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Giovanni MerlinoMariarosaria Valente
May 14, 2010·Anesthesiology·Mathieu RauxIsabelle Arnulf
Feb 16, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Richard P AllenMichael Calloway
Nov 22, 2011·Journal of the American Geriatrics Society·Vineet M AroraEve Van Cauter
Feb 2, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C-H LinR-M Wu

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Citations

Apr 16, 2021·Anesthesia and Analgesia·Shelley Hershner, Dennis Auckley
Apr 16, 2021·Anesthesia and Analgesia·Mandeep SinghDennis Auckley

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