Management of Small Bowel Neuroendocrine Tumors.

Surgical Oncology Clinics of North America
Aaron T Scott, James R Howe

Abstract

Small bowel neuroendocrine tumors (SBNETS) are slow-growing neoplasms with a noted propensity toward metastasis and comparatively favorable prognosis. The presentation of SBNETs is varied, although abdominal pain and obstructive symptoms are the most common presenting symptoms. In patients with metastases, hypersecretion of serotonin and other bioactive amines results in diarrhea, flushing, valvular heart disease, and bronchospasm, termed carcinoid syndrome. The treatment of SBNETs is multimodal and includes surgery, liver-directed therapy, somatostatin analogues, targeted therapy, and peptide receptor radionuclide therapy.

References

Mar 1, 1981·Current Problems in Surgery·J H Foster, J Lundy
Oct 19, 2000·World Journal of Surgery·U OhrvallG Akerström
Aug 23, 2001·British Journal of Anaesthesia·M A KinneyM A Warner
May 23, 2002·World Journal of Surgery·Per HellmanGöran Akerström
Jul 2, 2003·Journal of the American College of Surgeons·Juan M SarmientoFlorencia G Que
Feb 2, 1963·Lancet·E D WILLIAMS, M SANDLER
Dec 2, 2004·The American Journal of Gastroenterology·Irvin M ModlinMark Kidd
Dec 31, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Clarisse DromainEric Baudin
May 12, 2005·Gastroenterology·Irvin M ModlinMichael D Shapiro
Aug 19, 2007·Journal of Hepatology·Vincenzo MazzaferroJorgelina Coppa
Jun 21, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James C YaoDouglas B Evans
Aug 29, 2009·Neuroendocrinology·Rudolf ArnoldUNKNOWN European Neuroendocrine Tumor Society
Oct 27, 2009·Pancreas·Aaron I VinikMartyn Caplin
Mar 20, 2010·World Journal of Surgery·Kalle LanderholmJohannes Järhult
Jul 29, 2010·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Evan S GlazerSteven A Curley
Feb 26, 2011·Endocrinology and Metabolism Clinics of North America·Ben LawrenceIrvin M Modlin
Apr 19, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Juri RufHolger Amthauer
Jun 7, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Catherine Le RouxUNKNOWN Groupe d'étude des Tumeurs Endocrines (GTE)
Oct 11, 2011·World Journal of Surgery·Olov NorlénGöran Åkerström
Oct 26, 2011·Endocrine-related Cancer·Günter Klöppel
Mar 31, 2012·American Journal of Surgery·Kristen P MassiminoRodney F Pommier
Sep 13, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H SorbyeU Knigge
Dec 12, 2012·International Journal of Hepatology·Mark A Lewis, Timothy J Hobday
Nov 16, 2013·World Journal of Surgery·Olov NorlénPer Hellman
Dec 11, 2013·Endocrine-related Cancer·M FraenkelUNKNOWN Knowledge NETwork
Mar 25, 2014·Journal of the American College of Surgeons·J Philip BoudreauxEugene A Woltering
Apr 23, 2014·Annals of Surgical Oncology·Scott K ShermanJames R Howe
Jul 12, 2014·The New England Journal of Medicine·Martyn E CaplinUNKNOWN CLARINET Investigators

❮ Previous
Next ❯

Citations

Aug 31, 2020·Current Treatment Options in Oncology·Alexandra Gangi, Daniel A Anaya

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.