PMID: 9422180Mar 1, 1995Paper

Management of splenic trauma--changing concepts

European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine
E Reihneŕ, B Brismar

Abstract

During the last two decades the reported risk of overwhelming postsplenectomy infection (OPSI) has resulted in a conservative approach to splenic trauma, with the aim of splenic salvage. The appropriateness of this strategy is now questioned. The risk of OPSI varies with age and indication for splenectomy from less than 1% in adults to more than 4% in children. Pneumococcus is the causative agent in about 60% of cases. A prerequisite for splenic preservation procedures should be a haemodynamically stable patient without other intraabdominal injuries. The benefits derived from non-operative treatment of splenic salvage procedures may be overshadowed by the potential risk of transfusion-related bacterial and viral diseases. Polyvalent pneumococcal vaccines given early after splenectomy appear to reduce the incidence of OPSI substantially.

Citations

Apr 16, 2005·BMJ : British Medical Journal·Simon E J JanesBirgit Dijkstra
Jun 1, 2008·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Hugo T C VegerPaul J Bode
Nov 4, 1998·Alcoholism, Clinical and Experimental Research·B Brismar, B Bergman
Sep 9, 2008·Developmental and Comparative Immunology·Hermann-Josef Rothkötter
Oct 1, 2004·ANZ Journal of Surgery·David CaldicottPeter Day
Apr 9, 2014·Developmental and Comparative Immunology·K H MairF Meurens
Jul 1, 2005·Yonsei Medical Journal·Hyun Jung KimSe Ho Chang

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