Management of thyroid carcinoma arising from thyroglossal duct cyst

Laryngo- rhino- otologie
Jan HeidemannVeit Maria Hofmann

Abstract

Thyroid carcinoma presenting within thyroglossal duct remnants is rarely reported. Mostly diagnosis is received postoperatively after resection of the cyst. No definite agreement exists regarding the therapeutical management after excision of the cyst especially concerning the necessity of total thyroidectomy and radioiodine therapy. A series of five cases is presented and relevant literature is reviewed.A retrospective review of all patients with thyroglossal duct cyst carcinoma treated between 2002 und 2017 was performed. Out of 578 patients with a thyroglossal duct cyst in five (3 women and 2 men) in the age of 16-73 years (mean: 51, median: 56 years) a thyroidal carcinoma could be identified. All of them presented with a painless hyoidal swelling. Diagnosis was made in all cases after surgery, but in one case, malignancy was presumed in the preoperative MRI. Papillary thyroid carcinoma was found in all samples. Four of the patients underwent total thyroidectomy and radioiodine therapy, in two of them a neck dissection of medial and lateral compartment was performed. The last patient withdrew from further diagnostics and therapy.In all four samples, no carcinoma of the thyroidal gland or nodal metastasis was found. Due to th...Continue Reading

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