PMID: 11904023Mar 21, 2002Paper

Management strategy for adult patients with dorsal midbrain gliomas

Neurosurgery
David D YehRobert J Ernst

Abstract

Dorsal midbrain gliomas (DMGs) involving the tectum occur more commonly in children than in adults. These lesions are often indolent in nature, and patients require treatment only for obstructive hydrocephalus. Because limited information is available concerning adults with this type of lesion, we describe our experience and management strategy in adults with DMGs. We retrospectively reviewed the charts and magnetic resonance imaging scans of five adult patients (four men, one woman; mean age, 51.6 yr; range, 23-69 yr) who were treated from March 1992 to August 2001 for DMGs involving the tectum. The mean follow-up time for these patients was 71.4 months (range, 25-113 mo). We analyzed the data to determine the optimal treatment strategy and outcomes of patients with DMGs. Tumor volume was analyzed objectively with Scion Image software (Scion Corp., Frederick, MD) to document changes in volume and determine whether treatment strategy differed significantly with tumor size. Tumors in two of these patients were found incidentally, and three others presented with obstructive hydrocephalus. Magnetic resonance imaging scans demonstrated an isolated tectal glioma in one patient, tectal and tegmental (periaqueductal) gliomas in three ...Continue Reading

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Citations

Jun 7, 2018·Operative Neurosurgery·Alessandro PerinFrancesco DiMeco
Aug 8, 2018·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Gerard HersheweMicaela Koci
Jul 10, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mohsen Javadpour, Conor Mallucci
Oct 13, 2006·Current Treatment Options in Oncology·Jaishri O Blakeley, Stuart A Grossman
Nov 8, 2014·Acta neurochirurgica·Jonathan RothShlomi Constantini
Dec 17, 2014·Acta neurochirurgica·Amr Mohamed Nageeb El-ShehabyIgnatius Ngene Esene
Mar 21, 2013·Current Neurology and Neuroscience Reports·Sean A Grimm, Marc C Chamberlain
Jun 1, 2014·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Roberto Jose DiazMark G Hamiltonn
May 12, 2017·Journal of Korean Neurosurgical Society·Runchun LuYazhuo Zhang
Apr 3, 2009·Journal of Neurosurgery. Pediatrics·Shigeru YamaguchiYoshinobu Iwasaki
Aug 7, 2014·Journal of Neuro-oncology·Mueez WaqarMichael D Jenkinson
Apr 24, 2015·BMJ Case Reports·Annick KronenburgPierre Robe
Apr 15, 2005·Arquivos de neuro-psiquiatria·Ricardo RaminaWalter Oleschko Arruda
Jan 24, 2007·Journal of Neurosurgery·Chun Po YenLadislau Steiner
Apr 23, 2013·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Luxin Yin, Liwei Zhang

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