Managing a pregnant woman with a low platelet count

La Revue de médecine interne
O Pourrat, F Pierre

Abstract

The practical management of a pregnant woman with a platelet count below 150 x 10(9) per liter is very simple. A spurious thrombocytopenia must be discarded and isolated thrombocytopenia (begnin idiopathic gestational thrombocytopenia and idiopathic thrombocytopenic purpura) must be first differenciated from associated forms. It must be determined if thrombocytopenia appeared recently and therefore is directly specific of pregnancy. Severity is indicated by a very low platelet count and a high speed in lowering. Platelet count of the newborn must always be checked on ombilical cord blood at the time of the birth. Steroid therapy may be needed in some cases of idiopathic thrombocytopenic purpura, lupus or HELLP syndrome. Platelet counts must be checked, in every case, three months after delivery and in case of subsequent pregnancy. Low platelet count is a demonstrative example of the help the internist can afford to the obstetrician in the management of pregnancy-associated conditions.

References

Feb 25, 1978·British Medical Journal·C W RedmanL Beilin
Oct 20, 1990·Lancet·C KaplanG Tchernia
Jun 1, 1991·American Journal of Obstetrics and Gynecology·J N MartinR W Martin
Jan 1, 1990·American Journal of Obstetrics and Gynecology·J N MartinW L Wiser
Mar 1, 1990·American Journal of Obstetrics and Gynecology·R F Burrows, J G Kelton
Nov 1, 1982·Arthritis and Rheumatism·E M TanR J Winchester
Jul 1, 1993·British Journal of Haematology·G TcherniaC Kaplan
Jan 1, 1994·Obstetrics and Gynecology·R HuttM G Elder
Nov 11, 1993·The New England Journal of Medicine·R F Burrows, J G Kelton
Mar 1, 1993·British Journal of Obstetrics and Gynaecology·Y AhmedM G Elder
Dec 1, 1996·American Journal of Obstetrics and Gynecology·H MinakamiI Sato
Jan 15, 2000·Obstetrics and Gynecology·F BoehlenP de Moerloose
Aug 3, 2001·American Journal of Obstetrics and Gynecology·M B FausettR M Silver
Jun 5, 2002·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·M A BrownJ M Moutquin
Feb 18, 2003·British Journal of Haematology·UNKNOWN British Committee for Standards in Haematology General Haematology Task Force
Jun 26, 2003·American Journal of Obstetrics and Gynecology·Mark C ChamesBaha M Sibai
Oct 17, 2003·The New England Journal of Medicine·Melissa R ArbuckleJohn B Harley
May 26, 2004·La Revue de médecine interne·O Pourrat
Aug 5, 2004·American Journal of Obstetrics and Gynecology·Olivier PourratFabrice Pierre
May 28, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J M O'BrienJ R Barton
Nov 26, 2005·Clinical and Laboratory Haematology·K M BowlesT P Baglin
Jan 4, 2006·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Paulino Vigil-De Gracia
Mar 15, 2006·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Michal ParnasRonit Yerushalmi
Mar 16, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Olivier Pourrat, Fabrice Pierre
Apr 3, 2007·Obstetrics and Gynecology·Baha M Sibai
Oct 30, 2007·La Revue de médecine interne·B Godeau

❮ Previous
Next ❯

Citations

Nov 3, 2010·La Revue de médecine interne·P Philippe
Jan 10, 2009·La Revue de médecine interne·G d'YthurbideA Kettaneh
Aug 30, 2008·La Revue de médecine interne·O PourratG Magnin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.