Managing antibiotics wisely: a quality improvement programme in a tertiary neonatal unit in the UK

BMJ Open Quality
Vasiliki MakriSujoy Banerjee

Abstract

Microbial resistance to antibiotics is a serious global health problem compounded by antibiotic overuse and limited investment in new antibiotic research. Inappropriate perinatal antibiotic exposure is increasingly linked to lifelong adverse outcomes through its impact on the developing microbiome. Antibiotic stewardship may be the only effective preventative strategy currently available. As the first tertiary neonatal unit in the UK to collaborate in an international quality improvement programme (QIP) with Vermont Oxford Network (VON), we present the results of our antibiotic stewardship initiative. The QIP was officially launched in January 2016 and aimed to reduce antibiotic usage rate (AUR) by 20% of baseline by 31st December 2016 without compromising patient safety. A multidisciplinary team of professionals and parent representatives shared good practices and improvement strategies through international webinars and local meetings, devised uniform data collection methodology and implemented a number of carefully selected 'Plan-Do-Study-Act' cycles. Run charts were used to present data and, where appropriate, statistical analysis undertaken to compare outcomes. The QIP resulted in a sustained reduction in AUR from a baseli...Continue Reading

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Jan 8, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·V LambaM Balakrishnan
Feb 10, 2019·Pediatric Research·Rachel G GreenbergUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
May 26, 2021·Clinics in Perinatology·Sophie KatzHayden Schwenk
Jun 27, 2021·Trends in Microbiology·Dhrati V PatangiaR Paul Ross
Aug 5, 2021·Pediatric Quality & Safety·Kathleen E WalshCharles Bailey
Sep 5, 2018·Pediatrics·Dustin D Flannery, Karen M Puopolo

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