Managing Heavy Menstrual Bleeding in Women at Risk of Thrombosis

Clinical Obstetrics and Gynecology
Andrew Rivara, Andra H James


Management of heavy menstrual bleeding (HMB) in a woman with a history of thrombosis, or who is otherwise at high risk of thrombosis, or who takes medications for anticoagulation can present a challenge to health care providers. The goal of treating HMB is to reduce menstrual blood loss. First-line therapy is typically hormonal, and hormonal therapy can be contraindicated in women with a history of thrombosis unless they are on anticoagulation. As 70% of women on anticoagulation experience HMB, successful management of HMB may involve a modification in the anticoagulation or antiplatelet regimen, hormonal therapy tailored to the patient's situation, and/or surgical therapy.


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Oct 20, 2018·British Journal of Haematology·Victoria SpeedRoopen Arya
May 13, 2021·Research and Practice in Thrombosis and Haemostasis·Jan Beyer-Westendorf, Sandra Marten

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