Mandarin juice improves the antioxidant status of hypercholesterolemic children

Journal of Pediatric Gastroenterology and Nutrition
Pilar Codoñer-FranchVictoria Valls Bellés

Abstract

Oxidative stress has been linked to such degenerative diseases as atherosclerosis, and it has been suggested that increased dietary intake of antioxidants may reduce its progression. To determine the effect of mandarin juice consumption on biomarkers related to oxidative stress in hypercholesterolemic children. The diet of 48 children with plasma cholesterol >200 mg/dL and low-density lipoprotein cholesterol >130 mg/dL was supplemented for 28 days with 500 mL/day of pure (100%) mandarin juice (Citrus clementina Hort. ex Tan.). The composition of the mandarin juice was analyzed, and its antioxidant antiradical activity was evaluated in vitro. Malondialdehyde, carbonyl groups, vitamins E and C, erythrocyte-reduced glutathione, and plasma lipids were measured at the onset and at the end of the supplementation period. The paired Student t test was used to compare values before and after supplementation. Mandarin juice exerted a strong antioxidant effect mainly due to its high hydroxyl activity and, to a lesser extent, to its superoxide scavenger activity. At the end of the study, levels of the plasma biomarkers of oxidative stress were significantly decreased (malondialdehyde -7.4%, carbonyl groups -29.1%, P < 0.01), whereas the pl...Continue Reading

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Citations

Apr 21, 2011·Journal of Agricultural and Food Chemistry·Luigi MilellaGiuseppe Martelli
Apr 14, 2015·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Joël ConstansAnnie M Bérard
Jun 10, 2010·Acta Paediatrica·Pilar Codoñer-FranchVictoria Valls-Bellés
Jun 18, 2010·Cardiovascular Therapeutics·Pasquale Pignatelli, Stefania Basili
Aug 13, 2009·Pediatric Diabetes·Pilar Codoñer-FranchVictoria Valls-Bellés

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