Mandibular reconstruction: meta-analysis of iliac- versus fibula-free flaps

ANZ Journal of Surgery
Sarah LonieRamin Shayan

Abstract

Free vascularized bone flaps are widely recognized as the optimal reconstruction for patients who undergo mandibular resection. The fibula-free flap is currently considered the gold standard, workhorse flap for mandibular reconstruction. Although previous studies have analysed individual success of each flap type, few have compared iliac- and fibula-free flaps. A systematic review of the literature was conducted in line with the PRISMA protocol searching the PubMed and EBSCO databases. Twenty-four studies were included as per predetermined inclusion criteria. Double-arm random effect meta-analysis was conducted with STATA 12, and single-arm meta-analysis was conducted utilizing Meta-XL. The results of this meta-analysis confirm that there is no significant difference in total flap loss between fibula- and iliac-free flap reconstruction of mandibular defects. In terms of recipient site complication, there was a significantly higher risk of delayed healing and suture line breakdown in the iliac flap group (P = 0.05). Donor site complications showed a trend towards being higher in the fibula flap group. Osseointegrated dental implant loss in fibula flaps was higher than in iliac flaps (5.3% compared with 1.7%). Both iliac- and fib...Continue Reading

References

Jul 1, 1978·Annals of Plastic Surgery·R K Daniel
Feb 1, 1997·Plastic and Reconstructive Surgery·E D RoumanasJ Beumer
May 1, 1997·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J FerriJ Mercier
Jan 24, 1998·Archives of Otolaryngology--head & Neck Surgery·M L UrkenH F Biller
Jan 3, 2001·Seminars in Surgical Oncology·J J Disa, P G Cordeiro
Nov 17, 2001·Plastic and Reconstructive Surgery·A TakushimaY Kimata
Jul 27, 2002·Plastic and Reconstructive Surgery·David A Hidalgo, Andrea L Pusic
May 8, 2003·Acta otorrinolaringológica española·C Navarro CuéllarC Navarro Vila
Jan 12, 2005·Clinical Oral Implants Research·Franz-Josef KramerBernd Bremer
Jul 29, 2006·The Journal of Prosthetic Dentistry·Neal GarrettKrishan K Kapur
Sep 9, 2006·Atlas of the Oral and Maxillofacial Surgery Clinics of North America·Rui Fernandes
Apr 24, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ali GbaraFelix Blake
Jan 25, 2008·The Journal of Craniofacial Surgery·Mustafa YilmazAli Kizilkaya
Nov 4, 2009·The Journal of Craniofacial Surgery·Gwénaël RaoulJoël Ferri
Nov 15, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Johannes T M van GemertEllen M Van Cann
May 9, 2012·The Journal of Craniofacial Surgery·Massimo Politi, Corrado Toro
Sep 4, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Marcus GerressenAlireza Ghassemi
Feb 13, 2013·The British Journal of Oral & Maxillofacial Surgery·Thomas MückeMarco R Kesting
Apr 20, 2013·JAMA Otolaryngology-- Head & Neck Surgery·Devin J OkayMark Persky
Jul 3, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Xiao Feng LingNabil Samman
Sep 26, 2013·The International Journal of Oral & Maxillofacial Implants·Feng WangZhiyong Zhang

❮ Previous
Next ❯

Citations

Mar 4, 2019·Clinical Oral Investigations·Önder SolakogluHeidi Schwarzenbach
Jan 7, 2021·ANZ Journal of Surgery·Jason DiabJonathan Clark
Nov 25, 2020·The British Journal of Oral & Maxillofacial Surgery·Alexander K BartellaBernd Lethaus
Nov 5, 2020·Journal of Clinical Medicine·Francesco RicottaAchille Tarsitano
Apr 13, 2021·Journal of Stomatology, Oral and Maxillofacial Surgery·Stefano RiccioMohssen Ansarin
Oct 13, 2020·International Journal of Oral and Maxillofacial Surgery·L XiaY He
Jan 3, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Xiao-Hui ZhangTao Zhang
Nov 17, 2020·The Journal of Craniofacial Surgery·Amir M ZaidOsama Eldamshety
Jun 26, 2018·Surgical Oncology·Giovanni Dell'Aversana OrabonaLuigi Califano
Aug 14, 2021·International Journal of Oral and Maxillofacial Surgery·B GuoC Ma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
C Zhang
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Johannes T M van GemertEllen M Van Cann
Seminars in Plastic Surgery
Harvey ChimHung-Chi Chen
© 2021 Meta ULC. All rights reserved