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Manganese mutagenesis in yeast. A practical application of manganese for the induction of mitochondrial antibiotic-resistant mutations

Journal of General Microbiology

Oct 1, 1975

A PutramentW Prazmo

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Abstract

When yeast cells were incubated for 4 to 8 h in yeast extract-peptone-glucose medium, pH 6, containing 8 mM-manganese, and then plated on selective media, there was a strong induction of antibiotic-resistant mutations. Indirect evidence suggests that practically all resistant mutants se...read more

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Bacteriocidal Agents
Mitochondria
Hydrogen-Ion Concentration
Recombination, Genetic
Cytoplasmic Inheritance
Saccharomyces cerevisiae
Manganese
Clastogens
Antibiotic Resistance, Microbial
Cell Division Phases
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  • Manganese mutagenesis in yeast. A practical application of manganese for the induction of mitochondrial antibiotic-resistant mutations

    Journal of General Microbiology

    Oct 1, 1975

    A PutramentW Prazmo

    PMID: 464

    DOI: 10.1099/00221287-90-2-265

    Abstract

    When yeast cells were incubated for 4 to 8 h in yeast extract-peptone-glucose medium, pH 6, containing 8 mM-manganese, and then plated on selective media, there was a strong induction of antibiotic-resistant mutations. Indirect evidence suggests that practically all resistant mutants se...read more

    Mentioned in this Paper

    Bacteriocidal Agents
    Mitochondria
    Hydrogen-Ion Concentration
    Recombination, Genetic
    Cytoplasmic Inheritance

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