Mangiferin and naringenin affect the photostability and phototoxicity of sunscreens containing avobenzone

Journal of Photochemistry and Photobiology. B, Biology
Camila Martins Kawakami, Lorena R Gaspar

Abstract

Efficient UV-absorbing molecules are designed to protect against UV-light exposure. However, the development of photostable sunscreens is important to preserve the photoprotective efficacy and to prevent the formation of reactive oxygen species (ROS) and photodegradation products, which can promote phototoxic or photoallergic contact dermatitis. The aim of this study was to evaluate the effects of mangiferin and naringenin on the photostability and phototoxicity of sunscreens containing avobenzone. Cosmetic sunscreen formulations containing octocrylene (OCT), octyl methoxycinnamate (OMC) and avobenzone (AVO) were prepared and supplemented or not with mangiferin, naringenin, or with both compounds in combination. For photostability studies, samples of the formulations were spread onto glass plates, exposed to UVA radiation and then analyzed by high performance liquid chromatography (HPLC) to determine UV filters and the antioxidants recovery. The phototoxicity of the UV filters and antioxidants was evaluated using 3T3 fibroblast cultures that were subjected (or not) to irradiation according to OECD TG 432. The photostability studies demonstrated that AVO and naringenin showed the highest photodegradation when present in formulat...Continue Reading

References

May 1, 1997·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S C Sahu, G C Gray
Jul 5, 2003·Bioscience, Biotechnology, and Biochemistry·Gow-Chin YenShih-Li Huang
Mar 30, 2005·Environmental and Molecular Mutagenesis·Ganesh Chandra Jagetia, Venkatasubbaiah Ashokakumar Venkatesha
May 24, 2005·Skin Pharmacology and Physiology·C G J HaydenM S Roberts
Nov 18, 2005·International Journal of Pharmaceutics·L R Gaspar, P M B G Maia Campos
Jan 18, 2006·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Gilberto Lázaro Pardo-AndreuAnibal E Vercesi
Jan 31, 2006·Journal of Photochemistry and Photobiology. B, Biology·Elisabetta DamianiLucedio Greci
Apr 13, 2007·Journal of Photochemistry and Photobiology. B, Biology·Elisabetta DamianiLucedio Greci
Apr 25, 2008·Journal of the American Academy of Dermatology·Laurent Marrot, Jean-Roch Meunier
May 20, 2008·Free Radical Biology & Medicine·E VendittiE Damiani
Sep 23, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·L R GasparP M B G Maia Campos
Oct 28, 2009·Chemical Research in Toxicology·Isabella KarlssonAnna Börje
Apr 1, 2010·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Marisa MeloniBarbara de Servi
Apr 1, 2010·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Nadim A Shaath
Apr 1, 2010·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Virginie Lhiaubet-ValletMiguel Angel Miranda
Jul 21, 2010·Archives of Dermatology·Martine Avenel-AudranLudovic Martin
Aug 31, 2010·Talanta·Lorena Rigo Gaspar, Patricia Maria Berardo Gonçalves Maia Campos
Oct 5, 2010·International Journal of Dermatology·Deevya L NarayananJoshua L Fox
Feb 1, 2011·Fitoterapia·D ProcházkováN Wilhelmová
Feb 5, 2011·Journal of the American Academy of Dermatology·Divya R Sambandan, Desiree Ratner
Mar 26, 2011·Journal of Photochemistry and Photobiology. B, Biology·Antoinette PetrovaJeanine L Marnewick
May 26, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rui-Rui WangYong-Tang Zheng
Oct 12, 2011·European Journal of Nutrition·Lucía MárquezJuan C Leza
Jan 31, 2012·The British Journal of Dermatology·UNKNOWN European Multicentre Photopatch Test Study (EMCPPTS) Taskforce
Aug 22, 2012·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Lorena R GasparManfred Liebsch
Nov 1, 2012·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Lindsay R SklarIltefat Hamzavi
Jul 19, 2014·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Xue-Xuan FengZhi-Xiu Lin
Dec 24, 2014·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Carolina Gomes BenevenutoLorena Rigo Gaspar

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Citations

Feb 7, 2016·Journal of Photochemistry and Photobiology. B, Biology·Alena Rajnochová SvobodováJitka Vostálová
Mar 16, 2017·Photochemistry and Photobiology·Gagan ChhabraNihal Ahmad
Mar 18, 2017·Photochemistry and Photobiology·Alena Rajnochová SvobodováJitka Vostálová
Jan 8, 2021·Marine Drugs·Félix L Figueroa
Dec 31, 2020·International Journal of Molecular Sciences·Justyna PopiółElżbieta Pękala

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