Mania with and without depression in a community sample of US adolescents

Archives of General Psychiatry
Kathleen R MerikangasJules Angst

Abstract

There are limited data on the manifestations of mania in general community samples of adolescents. To present the prevalence and clinical correlates of mania with and without depressive episodes in a representative sample of US adolescents. Cross-sectional survey of adolescents using a modified version of the Composite International Diagnostic Interview. Ten thousand one hundred twentythree adolescents aged 13 to 18 years identified in household and school settings. Mania/hypomania with or without depression among those who met DSM-IV criteria for bipolar I or II disorder or major depressive disorder. Two and a half percent of youth met criteria for lifetime bipolar I or II disorder and 1.7%, for mania only. Twelve-month rates of mania with and without depression were 2.2% and 1.3%, respectively. There was a nearly 2-fold increase in rates of mania from ages 13-14 to 17-18 years. Mania with depression was associated with a greater number of all indictors of clinical severity including symptom number and severity, role disability, severe impairment, comorbidity, and treatment compared with depression alone, whereas correlates of mania were similar among those with mania with or without depression. The increasing prevalence of bi...Continue Reading

Citations

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